Hit 9

FA	RX(1); FLST(1); RX(8)

Reaction (1 of 1)

Reaction ID	267958
Reactant BRN	1858667
Reactant	1-phenyl-propan-2-ol
Product BRN	2041552
Product	(2-chloro-propyl)-benzene
No. of Reaction Details	8

Reaction Details (1 of 1)

Reaction Classification	Preparation
Reagent	phosphorus pentachloride
Comment	Handbook
Citation Pointer	1517727; Journal; Errera; GCITA9; Gazz.Chim.Ital.; 16; 1886; 322;

Reaction Details (2 of 1)

Reaction Classification	Preparation
Reagent	concentrated hydrochloric acid
Temperature	135
Comment	Handbook
Citation Pointer	1517727; Journal; Errera; GCITA9; Gazz.Chim.Ital.; 16; 1886; 322;

Reaction Details (3 of 1)

Reaction Classification	Preparation
Reagent	SOCl2
Citation Pointer	177968; Journal; Urry,W.H. et al.; JOCEAH; J.Org.Chem.; EN; 29; 7; 1964; 1663-1669;

Reaction Details (4 of 1)

Reaction Classification	Preparation
Reagent	PCl5
Temperature	0
Citation Pointer	1974; Journal; Pross,A.; Sternhell,S.; AJCHAS; Aust.J.Chem.; EN; 24; 1971; 1437-1447;

Reaction Details (5 of 1)

Reaction Classification	Preparation
Reagent	SOCl2, Py
Citation Pointer	178195; Journal; Shabtai,J.; Pines,H.; JOCEAH; J.Org.Chem.; EN; 29; 1964; 2408-2412;258427; Journal; Desai,V.R. et al.; JCSPAC; J.Chem.Soc.B; EN; 1969; 30-32;

Reaction Details (6 of 1)

Reaction Classification	Preparation
Yield	66 percent (BRN=2041552)
Reagent	thionyl chloride, Et3N
Solvent	diethyl ether
Time	30 min
Other Conditions	Ambient temperature
Citation Pointer	5842095; Journal; Gray, Nancy M.; Cheng, Brian K.; Mick, Stephen J.; Lair, Cecelia M.; Contreras, Patricia C.; JMCMAR; J.Med.Chem.; EN; 32; 6; 1989; 1242-1248;

Reaction Details (7 of 1)

Reaction Classification	Preparation
Yield	100 percent Chromat (BRN=2041552)
Reagent	Me3SiCl
Catalyst	BiCl3
Solvent	neat (no solvent)
Time	2 hour(s)
Temperature	80
Citation Pointer	5966321; Journal; Labrouillere, Mireille; Roux, Christophe Le; Oussaid, Abdelouahad; Gaspard-Iloughmane, Hafida; Dubac, Jacques; BSCFAS; Bull.Soc.Chim.Fr.; FR; 132; 1995; 522-530;

Reaction Details (8 of 1)

Reaction Classification	Preparation
Yield	80 percent (BRN=2041552)
Reagent	silica chloride
Solvent	CCl4
Time	30 min
Temperature	25
Citation Pointer	6041315; Journal; Mohanazadeh, F.; Momeni, A. R.; OPPIAK; Org.Prep.Proced.Int.; EN; 28; 4; 1996; 492-494;

Reference (1 of 8)

Citation Number	1974
Document Type	Journal
Authors	Pross,A.; Sternhell,S.
CODEN	AJCHAS
Journal Title	Aust.J.Chem.
Language Code	EN
(Series) Volume	24
Publication Year	1971
Page	1437-1447

Reference (2 of 8)

Citation Number	177968
Document Type	Journal
Authors	Urry,W.H. et al.
CODEN	JOCEAH
Journal Title	J.Org.Chem.
Language Code	EN
(Series) Volume	29
Number	7
Publication Year	1964
Page	1663-1669

Reference (3 of 8)

Citation Number	178195
Document Type	Journal
Authors	Shabtai,J.; Pines,H.
CODEN	JOCEAH
Journal Title	J.Org.Chem.
Language Code	EN
(Series) Volume	29
Publication Year	1964
Page	2408-2412

Reference (4 of 8)

Citation Number	258427
Document Type	Journal
Authors	Desai,V.R. et al.
CODEN	JCSPAC
Journal Title	J.Chem.Soc.B
Language Code	EN
Publication Year	1969
Page	30-32

Reference (5 of 8)

Citation Number	1517727
Document Type	Journal
Authors	Errera
CODEN	GCITA9
Journal Title	Gazz.Chim.Ital.
(Series) Volume	16
Publication Year	1886
Page	322

Reference (6 of 8)

Citation Number	5842095
Document Type	Journal
Authors	Gray, Nancy M.; Cheng, Brian K.; Mick, Stephen J.; Lair, Cecelia M.; Contreras, Patricia C.
CODEN	JMCMAR
Journal Title	J.Med.Chem.
Language Code	EN
(Series) Volume	32
Number	6
Publication Year	1989
Page	1242-1248

Reference (7 of 8)

Citation Number	5966321
Document Type	Journal
Authors	Labrouillere, Mireille; Roux, Christophe Le; Oussaid, Abdelouahad; Gaspard-Iloughmane, Hafida; Dubac, Jacques
CODEN	BSCFAS
Journal Title	Bull.Soc.Chim.Fr.
Language Code	FR
(Series) Volume	132
Publication Year	1995
Page	522-530

Reference (8 of 8)

Citation Number	6041315
Document Type	Journal
Authors	Mohanazadeh, F.; Momeni, A. R.
CODEN	OPPIAK
Journal Title	Org.Prep.Proced.Int.
Language Code	EN
(Series) Volume	28
Number	4
Publication Year	1996
Page	492-494