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2C-I is a phenethylamine somewhat similar in effects to 2C-B. It became available on the grey markets in 2002, but distribution dropped off after a series of DEA busts in 2004 and the prosecutions of vendors selling research chemicals for recreational use. It is available primarily in powder form--though some pressed tablets have been seen--and is generally taken orally.
A standard oral dose of 2C-I is between 10-25 mg. Recent reports suggest that 2C-I is just slightly more potent than 2C-B (slightly less material needed for the same level of effects).
Price #
2C-I is sold at $300-500 USD per gram retail, and $50-200 USD per gram wholesale (2011).
2C-I is a Schedule I controlled substance in the United States meaning that possession or distribution without a DEA license is illegal. It became controlled under federal law in the US in 2012. 2C-I is scheduled in Germany and Denmark, but not in the European Union (EU).
2,5-Dimethoxy-4-Iodophenethylamine (2C-I) is a synthetic chemical phenethylamine related structurally to 2C-B.
Pharmacology #
Pharmacology Summary Needed.
Production #
The bulk of available 2C-I is primarily produced by experienced chemists in commercial labs.
History #
2C-I first gained public awareness after the publication of PiHKAL by Alexander & Ann Shulgin.
Terminology / Slang #
The Substance:
The Experience:
Onset #
Depending on how much and how recently the user has eaten, oral 2C-I takes between 45-75 minutes to take effect. On a full stomach, onset can be considerably slower.
Duration #
The primary effects of 2C-I last approximately 5-8 hours when taken orally.
Visual Effects #
Visuals Summary Needed.
Problems Summary Needed.
Contraindications #
  • Do not take 2C-I if you are currently taking an MAOI. MAOIs are most commonly found in the prescription anti-depressants Nardil (phenelzine), Parnate (tranylcypromine), Marplan (isocarboxazid), Eldepryl (l-deprenyl), and Aurorix or Manerix (moclobemide). Ayahuasca also contains MAOIs (harmine and harmaline). 2C-I and MAOIs are a potentially dangerous combination. Check with your doctor if you are not sure whether your prescription medication is an MAOI.
  • Do not operate heavy machinery. Do Not Drive.
  • Individuals currently in the midst of emotional or psychological upheaval in their everyday lives should be careful about choosing to use psychedelics such as 2C-I as they can trigger even more difficulty.
  • Individuals with a family history of schizophrenia or early onset mental illness should be extremely careful because psychedelics have been known to trigger latent psychological and mental problems.
Addiction Potential #
2C-I is neither physically addicting nor likely to cause psychological dependance. Withdrawal effects following discontinuation have not been reported. As with most substances, some people will use it more frequently than they are comfortable with. There is a short period of tolerance after 2C-I use. Using 2C-I two days in a row is likely to lead to a diminished experience the second day, though spaced 5-7 or more days apart, this effect is nearly non-existent.
Long Term Health Problems #
Long Term Health Problems Summary Needed.
Risk of Death #
Risk of Death Summary Needed.
Erowid Basics pages are summaries of data gathered from site visitors, government documents, books, websites, and other resources. We do our best to keep this information correct and up-to-date, but the field is complex and constantly changing. Information should always be verified through multiple sources.