Plants - Drugs Mind - Spirit Freedom - Law Arts - Culture Library  
Review Erowid at
Help us be a "Top Rated Nonprofit" for the 12th year in a row
and spread info about psychoactive drugs, health, culture, & policies.
("Share Your Story" link. Needs quick login creation but no verification of contact info)
by Erowid
1951 First published paper documenting the synthesis of methaqualone by Kacker and Zaheer, along with a number of other related compounds. 1  
1955 Methaqualone was first synthesized in India by M.L. Gujral and was soon being marketed as a non-addictive sleeping pill. 2, 3   [Details]
1960 Methaqualone is sold by the Boots company under the names Melsed and Melsedin and by Marck as Renoval. 2  
1965 Methaqualone is sold by Roussel labs in combination with an antihistamine under the name Mandrax. 2  
Late 60s Methaqualone becomes a commercial success in the United States where it is sold under the name Quaalude. It also becomes a popular street drug. 2  
1971 Methaqualone becomes regulated in Britain under the UK Misuse of Drugs Act due to its increasing popularity as a recreational drug.   
1973 Methaqualone is placed in Schedule II in the United States making it difficult to prescribe and illegal to possess without a prescription.   
Early 80s Methaqualone is withdrawn from the market in Britain due to its addictive qualities.   
1984 Methaqualone is moved to Schedule I in the United States, making it illegal to buy, sell, or possess.   

  1.   IK Kacker, Zaheer SH. Potential Analgesics. Part I. Synthesis of substituted 4-quinazolones. J. Ind. Chem. Soc. 28 (1951), pp. 344346.
  2.   Rudgley R. The Encyclopaedia of Psychoactive Substances. Thomas Dunne Books, 1998.
  3.   Snyder SH, Lader MH. "The Encyclopedia of Psychoactive Drugs: Methaqualone, the quest for oblivion."