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Methylone
Bits & Pieces
by Erowid

The "Bits & Pieces" section is intended for random snippets of information which don't fit
easily elsewhere and/or which have been newly added, but not yet carefully categorized.


  • Two Different Chemicals Called Methylone
    The name "methylone" is used in reference to two completely different chemicals. It's not yet known which was named first. One is the psychoactive chemical 2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (an empathogen similar to MDMA), and the other is a trademarked brand name for methylprednisolone (an injectable adrenal corticosteroid used in the treatment of arthritis-related joint pain).

  • Distrust of Methylone in E.U. Underground Therapy Community
    According to a source Erowid that considers reliable, a group of physicians in the European Union who have conducted underground therapy sessions with entheogens/empathogens rejected the use of methylone as a therapeutic agent in their work because of problems they attribute to it.

    Out of approximately 250 clients given methylone in a semi-controlled setting ("psychedelic therapy" with a sitter present), three were hospitalized after they developed severe urinary tract infection symptoms following a session. This was notable because these people didn't have histories of UTI. Two were in their mid-30s, one was in his 60s; all were male; all took doses considered to be standard (non-excessive) for this material.

    Outside of the setting described above but still in a home setting (i.e., not a over-heated dance/party), the physician group who observed the three cases above were made aware of two deaths following ingestion of standard doses of methylone. One of these subjects was in a group setting; others in the group noticed the subject stepping away and appearing confused. He later died of undisclosed causes. One of these two deaths was not formally associated with methylone because having reported this information was believed to have the potential of negatively impacting a life insurance payout.

    The physician who personally contacted Erowid regarding the information above would not speak on the record and would not permit follow-up contact, so no further details (such as medical history, food/drug intake, etc.) for the victims are available. This doctor and his/her colleagues have speculated that a percentage of individuals may be genetically predisposed toward some action of methylone that can lead to UTI and/or to severe overheating.