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Michael Mithoefer
Photo by Jon Hanna, 2006
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Michael C. Mithoefer
Michael Mithoefer spent a decade of his early career as a board certified emergency medical physician. He is also certified in internal medicine, and in 1991 he became certified in psychiatry. He has had his own private practice of psychiatry and clinical research in Mount Pleasant since 1995. He is also a holotropic breathwork facilitator, and is certified in levels I and II of Eye Movement Desensitization and Reprocessing, an integrative form of psychotherapy.

On November 2, 2001, Mithoefer (as principal investigator) and his wife Annie (a psychiatric nurse) obtained FDA approval to run a clinical trial in the United States giving MDMA in combination with psychotherapy to treat chronic, treatment-resistant post-traumatic stress disorder in 12 patients. The first experimental session of his phase II clinical trial happened on April 16, 2004, and the last experimental session took place on July 18, 2008. The trial showed MDMA to be a safe and effective adjunct to psychotherapy for the small group of patients included in the study.

Author of (Book Chapters)
  • MDMA in the Treatment of Posttraumatic Stress Disorder, in: H. Jungaberle, P. Gasser, J. Weinhold (Eds). Therapie mit psychoaktiven Substanzen - Praxis und Kritik der Psychotherapie mit LSD, Psilocybin und MDMA. Verlag Hans Huber (2008)
  • MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder, in: M.J. Winkelman and T.B. Roberts (Eds). Psychedelic Medicine: New Evidence for Hallucinogenic Substances as Treatments. Greenwood Publishing, pages 155-76-25 (2007)
  • Informed Consent for Holotropic Breathwork, in: K. Taylor (Ed). Exploring Holotropic Breathwork: Selected Articles from a Decade of the Inner Door. Hanford Mead (2003)
  • Some Anecdotes of Healing and Holotropic Breathwork [with T.M. Brightman, T.A. Tepfer, and M. Rossler], in: K. Taylor (Ed). Exploring Holotropic Breathwork: Selected Articles from a Decade of the Inner Door. Hanford Mead (2003)
  • Author of (Articles)
  • Response to: Parrott AC, Buchanan T, Heffernan TM, Scholey A, Ling J, Rodgers J (2003) Parkinson's Disorder, Psychomotor Problems and Dopaminergic Neurotoxicity in Recreational Ecstasy/MDMA Users. Psychopharmacology 167(4):449-450 [with H.R. Sumnall, L. Jerome, and R. Doblin]. Psychopharmacology 171:229-30 (2004)
  • MDMA ("Ecstasy") and Neurotoxicity [with L. Jerome, R. Doblin]. Science 1504-5 (June 2003)
  • The Physiology of Hyperventilation. The Inner Door 9(2):1,4-6 (1997)
  • Pulmonary Gas Exchange in Andean Natives at High Altitude [with J.C. Mithoefer, J.E. Remmersa, and G. Zubietaa]. Respiration Physiology 15(2):182-9 (1972)
  • Videos
  • Ecstasy Cures PTSD, CNN (November 2008)
  • Audio
  • Ecstasy, The Peace Drug?, NPR (November 2007)
  • MDMA-Assisted Psychotherapy for Post-Traumatic Stress Disorder, Psychedelic Salon (April 2007)