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Beyond Tollerance Reduction
Memantine, Tobacco, Cannabis & Amphetamines (Adderall)
by Clyde T.
Citation:   Clyde T.. "Beyond Tollerance Reduction: An Experience with Memantine, Tobacco, Cannabis & Amphetamines (Adderall) (exp101734)". Mar 15, 2019.

T+ 0:00
20 mg oral Pharms - Memantine (pill / tablet)
  T+ 0:30 5 mg oral Amphetamines (pill / tablet)
  T+ 1:15 1 cig. smoked Tobacco  
  T+ 1:15 3 hits smoked Cannabis (plant material)
  T+ 0:00   repeated smoked Tobacco  


To give background on this report- I am very familiar with amphetamines, especially adderall. Having been prescribed it for a few years my tolerance was higher than most. I would take doses around 140mg on adderall and 250mg on vyvanse with little effect. I discontinued it’s use about 4 months prior to this event.

I had been taking memantine 40mg daily for around 6 months and was aware of the tolerance reducing effect on amphetamines.

I was a daily cannabis/tobacco smoker at the time.

(6:15 PM) Before I leave for my friends house I take my memantine (20mg) and slip a 10mg IR adderall into my pocket. At this point I was still debating if I should take it.

(6:35) I get to my friends house in good spirits, nothing unusual. I’m getting taken to the cleaners playing video games so I decide to take half of the adderall orally (6:45). We keep playing for a while, I still get crushed.

(7:30 ish) I begin to feel the mild onset and my game picks up, but at the same time people are grinding bud and packing bowls, so we migrate outside. I proceed to roll a cigarette and smoke it.

One of my friends starts talking about his rolling machine- I think I roll pretty well but that thing rolls them FAT. I ask for one but I’m craving cigarettes so bad I roll another and smoke the majority of it before he finishes. All while this is going on the bong gets passed around. I took about 3 rips before I started smoking the cigarette he made.

Give or take it’s likely around (8:10) when I start to smoke the submarine which is this cigarette. I smoke it slow, as I start to feel a little off- dehydrated most likely. It’s a familiar feeling but it rapidly gets more intense to the point that I had to ask my friend to get me water ASAP, as I did not feel comfortable getting up myself.

I smoked about half the cigarette before I dropped it into the ashtray. If that can provide an idea for time. Things became dampened visually and I was seeing spots. It was taking to long to get the water so in an almost panicked, desperate state of slow moving dehydration I got up and moved 4 feet towards the doorway. My friend handed me the water- looked concerned and told me to come inside. I was already moving that way- 2 more feet- I’m in the doorway and I feel as if a cyclone is moving from my feet up my legs. I look down, see and feel my legs shake and buckle. I thought to myself, “oh shit” as the cyclone feeling got to the top of my legs/hips.

I blank out. Darkness. Very peaceful, serene. I am completely disconnected from whatever’s going on, I was in the best state of being I have ever experienced.
I blank out. Darkness. Very peaceful, serene. I am completely disconnected from whatever’s going on, I was in the best state of being I have ever experienced.
I was still conscience, in some sense. I could think freely but there was no transfer of how I got into that state. Or I simply didn’t care. I just accepted it. Enjoyed it.

Slowly, a dull blue light starts to emerge from the “bottom” and grows gradually upwards into what I can only describe as a silhouette. As it got larger and more pronounced white was spreading from the inside out and I hear something in the distance- I open my eyes and in a rush of blurry conscience my hearing goes from far away/muffled to normal while hearing “Clyde- Clyde. You awake? You ok man”?

I’m laying on my back inside the doorway, my friend on his knee next to me. I slowly sit up and look around, “dude i just tripped the fuck out- did I pass out”? My head hurts in a weird way so I assume I hit it on the way down, and my lip also hurts. They tell me I fainted, give me water and I walk over and sit down on the couch next to the TV. Some of them leave but I ask to stay a bit longer till the headache passes somewhat and he says ya so we start to play video games. I keep drinking water between deaths and I’m doing remarkably well. Better than before. Especially for just blacking out.

[Erowid Note: Driving while intoxicated, tripping, or extremely sleep deprived is dangerous and irresponsible because it endangers other people. Don't do it!]

I think he had to meet the other guys somewhere so I left around (9:00) and drove home. When I got in my car I examined my lip. I didn’t think it quite fit the bill for hitting the door handle on the way down. I examined the marks and moved it around a bit and it appeared that it had to be curled up somewhat and it fit more like bite marks.

When I got home around (9:10) the headache had almost completely faded. I felt as though I had total mental clarity and control. In the most honest comparison I can make it felt like the movie limitless. Describing it any other way would be difficult.

The following 36 hours were clear headed above all and the highest mental agility I have ever experienced.
The following 36 hours were clear headed above all and the highest mental agility I have ever experienced.
Fluid thought, perfect memory, detailed recall of my past- I didn’t commit much else to memory but outliving the afterglow of the drug was an overwhelming sense of self worth and importance. That lasted about a week.

However the following day I talked with all my friends that witnessed it and confirmed it was really a 15 second seizure.

Exp Year: 2013ExpID: 101734
Gender: Male 
Age at time of experience: 18 
Published: Mar 15, 2019Views: 5,979
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Cannabis (1), Tobacco (47), Amphetamines (6), Pharms - Memantine (309) : Small Group (2-9) (17), Health Problems (27), Difficult Experiences (5), Combinations (3), General (1)

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