Long-Acting Induced Mania
Phenibut & Buproprion
Citation:   Gungadin. "Long-Acting Induced Mania: An Experience with Phenibut & Buproprion (exp104103)". Erowid.org. Sep 21, 2019. erowid.org/exp/104103

200 mg oral Pharms - Bupropion (daily)
  3 g oral Smarts - Phenibut (capsule)
I have experience with a wide range of psychoactive substances - traditional (shrooms, lsd, mdma, cocaine, ketamine etc.), prescription (benzos, opiates, etc.), ethnobotanical (lsa, yarrow, kratom, siniquiche, etc.), and rc (methoxetamine, 6APB, etc.). So I know the difference between placebo and real effects. This stuff is absolutely not just a placebo.

I tried phenibut in the past at lower dosages, as a simple mood booster, and hadn't really noticed any effects, so I had written the substance off. However, yesterday I decided to try it again, after reading some reports. The last time I tried it was before I started taking 200mg/day buproprion; buproprion is a known CYP2D6 enzyme inhibitor, which means it can increase the bioactivity of other substances. Not sure how much that was in play in this case.

I took exactly 3g (in 500mg pill form, which is pretty convenient) at around 7pm, as I had read that it had somewhat of a long onset. Somehow, though, I failed to understand *how long* the onset really is.
I failed to understand *how long* the onset really is.
It was over four hours before I started feeling anything appreciable, and five before I had really come up. It is now 9:30am the next day, and I am still definitely high, although I'm (maybe?) starting to come down. The high is not debilitating for work, conversation, writing, etc., but I wouldn't try to drive on it. Fortunately, I don't have to be anywhere for a while.

I would describe the high as pretty similar to low-dose kratom, in the sense that it increased energy and motivation and caused some inebriation (motor skills degradation, mild euphoria, slight visual 'tracking' like alcohol). It feels very much like a manic state, with all the plusses and minuses of that condition. So, a giddy sense of possibility, increased talkativeness, physical energy / desire for exercise, increased libido, and a generally expansive, empathetic mood for the positives; decreased inhibitions and increased likelihood of poor decision-making (unnecessary purchases, sexual promiscuity, etc.) for the negatives. I also awoke with a slight headache, but I've been having those lately anyway, probably due to dehydration (I've been doing a ketogenic diet, which can cause that.) I stayed up late last night playing guitar, which I haven't done for a while, and woke up in the night to urinate feeling very inebriated (stumbling, even). This morning, I awoke still quite inebriated, with a distinct desire to 'do all the things' (including writing this very long trip report, apparently). I felt especially loving toward my partner, and had vastly increased energy for my morning walk -- I actually had to restrain myself from running, in stark contrast to the day prior, when I felt like I was dragging myself down the street.

Overall, a very positive experience. I have the sense that, like kratom, tramadol, and other mood-boosting substances, I may end up paying for this later with increased irritability and/or exhaustion; a friend of mine refers to it as 'borrowing from tomorrow'.

Definitely not something to take more often than once a week, in my view. The next time I try it, I may take it in the morning so I have a chance to enjoy the effects all day.

Exp Year: 2014ExpID: 104103
Gender: Male 
Age at time of experience: 36
Published: Sep 21, 2019Views: 4,101
[ View PDF (to print) ] [ View LaTeX (for geeks) ] [ Swap Dark/Light ]
Smarts - Phenibut (379), Pharms - Bupropion (87) : Medical Use (47), Combinations (3), Various (28)

COPYRIGHTS: All reports copyright Erowid.
TERMS OF USE: By accessing this page, you agree not to download, analyze, distill, reuse, digest, or feed into any AI-type system the report data without first contacting Erowid Center and receiving written permission.

Experience Reports are the writings and opinions of the authors who submit them. Some of the activities described are dangerous and/or illegal and none are recommended by Erowid Center.

Experience Vaults Index Full List of Substances Search Submit Report User Settings About Main Psychoactive Vaults