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Our Experiment
Mirtazapine & Cannabis
Citation:   Tripponeer_K. "Our Experiment: An Experience with Mirtazapine & Cannabis (exp106698)". Erowid.org. Feb 22, 2025. erowid.org/exp/106698

 
DOSE:
T+ 0:00
225 mg oral Pharms - Mirtazapine (pill / tablet)
  T+ 1:24 2 hits smoked Cannabis (flowers)
BODY WEIGHT: 150 lb
So, as a little background info before we embark on this journey, I have extensive experience with cannabis and some with a handful of other substances, but my only experience with a psychedelics is DMT and I had a rather high tolerance. I’ll be “tripping” at my friend B’s house with him, S, and A and E will be “trip sitting”, really just being there while not taking it themselves. B and S have more experience with hallucinogens and psychedelics then me as well. We are in B’s nice big open furnished basement, he lives on a hill so we can look out onto his driveway and the river. It was night at the time though. His mom had left for a few days a couple hours prior.

+0:00 B, S, and I just took a recreational dose of Mirtazapine, Remeron. I took 5 45 mg pills and they each consumed 3.5.

+0:45 A car pulls up B’s driveway, he hasn't even finished taking all of his dose yet (he hates pills) as he exclaims, “fuuuck... who's pulling up my driveway” great. S and I just took ours, no turning back now, and we already realized the slight potential for a bad trip with such an unknown substance (for our purposes at least).

+1:00 Turns out it’s just his mom, who was supposed to be gone but we all feel comfortable with her being here, it shouldn’t effect anything. Our experiment was not motivated by her being gone, only a coincidence.

+3:00 We debate smoking some cannabis, A & E are going to regardless, but the three tripponeers can’t decide, I know that it has the potential to sober me up as it has for pretty much any other substance I’ve combined it with. We decide to wait until A & E smoke and we’ll decide then.

+10:00 Me and B both agree we might feel a slight headache, it could be total placebo, he notes a feeling of dehydration. At this point we are doing pretty much what we always do in his room, sitting around, playing on phones. I certainly feel a weird anxiety, maybe its just excitement. Who knows, I have fairly severe Generalized Anxiety Disorder (that mirtazapine did not affect/ help with) as is.

+19:00 I think I'm beginning to feel something. S agrees but can't put a finger on it and says he “feels it at the tip of his head.” B still just feels dehydrated, just to lazy to go upstairs for water. I feel something slightly similar to alcohol, just a little inebriating, pleasant to be honest, a slight warm euphoric body tingle that reminds me of when oxy first stars making its way into your system, but just barely. A & E also went to smoke and we stayed in. Before A left we was reading some dosage information where 200mg was the very high, heavy dosage end, and some where it talked about the effects and how it could be considered more a deliriant in subjective effects and that deliriants are terrifying and can end badly. Thanks man, keeping that anxiety in check.

+33:00 We definitely feel it, indescribable to be honest. S’s eyes feel heavy, B feels lightheaded, they're both very drowsy, I’m not as sedated, I also have some fucking crazy sleeping problems as well though, so use them as a measure for being tired. I think it is primarily sedative though. It’s really hard to say this for sure however, because my dose was different from theirs, and I simply don’t get tired easy, often, etc. It did not however help me actually sleep.

+36:00 I feel warm as if from alcohol. I also have that weird effect it gives that feels like tracers, but it's more like a ghosting effect when I move my head. This effect grew, but it was more like a whole vision tracer/ blur thing.

+49:00 We just played some foosball to try and stay awake as the sedative effects were becoming a bit stronger. We all felt incredibly heavy, so much so that it wasn't like being sleep deprived but clearly a unique feeling because of the mirtazapine. Motor skills had diminished quite a bit by now. I could still hold it together, but playing was still hard. When we finished, I sat down and realized it felt amazing. I was so tired and comfy, even euphoric for sure. The aforementioned ghosting effect is stronger I also realized that things were starting to move around, just very minor shifting and shaking. A water bottle on the table in front of me (far enough away from the wall behind it that they required separate depths of field) began to sort of just wiggle around and stand out to me quite prominently. As I write this I realize the keys on my laptop, backlit, are beginning to have a tracer effect. It's really cool, but way too slight for now to get lost in or anything.

+55:00 I’m starting to notice walls melt, move etc. I did however notice after studying it, that the visuals aren't random. They followed the grain of the wood walls for example. B’s walls are awesome natural wood with swiss cheese looking knots all over, great for tripping apparently (as B and I found out). But the effects are really odd, when looking at a fire detector, the ceiling around it began to sort of swim around like a liquid. Now, this effect was especially weird because it still wasn't super strong overall. There weren’t crazy visual or anything close, only when I studied a certain spot or object.
the effects are really odd, when looking at a fire detector, the ceiling around it began to sort of swim around like a liquid. Now, this effect was especially weird because it still wasn't super strong overall. There weren’t crazy visual or anything close, only when I studied a certain spot or object.
But it was was so weird, it seemed to defy any logic about how it was occurring. I’ll elaborate, I first noticed it on the walls, where a perfect square section of the wall, was the only part moving. Not the wall around it, or even directly next to the edge of the “square.” It went somehow with the grain of the wood and the planks perfectly as well.

This is what caused me to realise a similar effect on the fire detector. So, a perfect, roughly 2 foot (diameter), circle of ceiling around the alarm was moving, like on the wall, with defined edges. Only this time, I wasn't staring straight at it, level like I was with the wall. The detector was across the room so I was seeing at an angle, it was an ellipse not a circle. What was absolutely baffling was that the visuals surrounding it played by the rules of the angle of my perception as well. It was as if the actually wood, in a perfect 1 foot radius around the detector was moving and breathing. And no matter how I looked at it, from whatever angle, anywhere in the room, the visuals “adapted”. It's like the wood was actually doing what I saw in that set little circle rather than a subjective drug induced visual effect. It was fascinating.

+78:00 People showed up, and then they left, this annoyed me a lot as they came to give A a bottle of alcohol, and then overstayed their welcome and were just way too much for me to be honest. I wanted them out. The effects haven't heightened much. We are going to smoke a few bong packs outside.

+84:00 2 sizeable hits each off a beaker bong with only choice chronic later and my friends had decided they were hitting the hay. The effects weren't changing any; however, we did all note that the outside world looked some kind of hellish and definitely off. It was dark we couldn't see much beyond range of the light on his front porch. Shadows were dancing, I kept thinking I'd seen something as well, off in the dark, faint, but human. I realized it could be shadow people. We went inside soon after, for me at least the cannabis had little effect but to calm my anxiety. It’s a medicine for me, and as soon as I smoked I felt no more worries about the drug.

+85:00 Everyone's in bed, A & E left, S is out cold but me and b aren't quite finished. I get slight CEV’s but they are not pleasant. They are extremely brief (fractions of a second), and are composed of a sharp harsh tone in my ears and an incredibly bright flash of some color. Fuck that, open them eyes up. I was looking at a dark spot, probably a wall, when I suddenly saw an orange, neon triangle draw itself super quickly, then a few more that just appeared and flew around rather than drawing themselves. I remember looking for more CEV’s or geometry and not seeing much. I laid awake for awhile as I'm accustomed to and eventually fell asleep to their snoring.



Exp Year: 2015ExpID: 106698
Gender: Male 
Age at time of experience: 18
Published: Feb 22, 2025Views: Not Supported
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Pharms - Mirtazapine (311), Cannabis (1) : General (1), First Times (2), Combinations (3), Glowing Experiences (4), Families (41), Guides / Sitters (39), Relationships (44), Small Group (2-9) (17)

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