Nice, But Not A Psychedelic
Citation:   Pfafffed. "Nice, But Not A Psychedelic: An Experience with 4-MeO-MiPT (exp111805)". Apr 10, 2018.

T+ 0:00
15 mg oral 4-MeO-MiPT (powder / crystals)
  T+ 0:40 4 mg oral 4-MeO-MiPT (powder / crystals)
(4-MeO-MiPT / ~20mg) - First Time - 'Nice, But Not A Psychedelic'

[This is not 4-HO-MiPT or 5-MeO-MiPT, two much more common tryptamines]

Background: Experienced with dozens of tryptamine, phenethylamine, and lysergamide psychedelics, as well as quite a few arylcyclohexylamine and other dissociatives, RC stimulants, and depressants, as well as some stranger botanical and RC odditites.

Currently: Physically tired, a little sunburned, a little dehydrated from a day hiking in the woods with new friends. Feeling upbeat and happy. Felt low physically yesterday due to sleep deprivation, but feel much better today. I have no tolerance to psychedelics, and the only drugs I've had today were caffeine. I did ingest some herbs (ashwagandha, reishi, licorice, and turmeric.) Happy to be home relaxing with my friend. Ate well today, but not a ton. Two hours ago, I had a very light snack of a bag of bugles and some iced tea, so my stomach is probably empty. I've also had the makings of a headache all day that never decided to manifest.

I hope that this material works out as a light, easy-going, short-acting erotic evening enhancer. I love *5*-MeO-MiPT, but it's long and gives me strong cross tolerance--it'd be great if this was a viable alternative. TBH, I'm not horny now, but I might feel differently when I wind down and have a shower.

Since there's no reagent data on this, I scraped off a ~1mg dose of this material three days ago to test orally in case it was a different, potent drug as its provenance is not entirely reliable. No effect was noticed.

7:30 PM Weighed out 15mg (+/- 5mg as scale was acting up despite calibration) of material sold as 4-MeO-MiPT and parachuted it. Plan to test the waters from here, maybe take another 5mg after I get a feel for it.

7:42 - Alert. Subtle. Going to shower.

8:04 - Possibly at a +, but just barely. I feel some warmth and tryptamine weirdness in my body, a slight headspace alteration. On balance, more unpleasant than pleasant, but too mild to be anything at all. I feel a little flutter of stimulation/anxiety like the feeling of jitters the time before you have sex with a new partner, but very mild. I also detect a bit of impulsivity as if I have some alcohol disinhibiton.

Thinking about taking the 5mg booster, although it's possible that I'm still coming up. I've seen it written, though, that impatiently redosing *5*-MeO-MiPT can keep you trapped in the early euphoric stages, preventing you from reaching the later psychedelic ones. Not sure if that makes any difference with this material, especially with its short duration.

8:10 - Take 4mg booster. Hands are tremory

8:11 - Rise up to a ++ almost immediately after dosing. Whoops, can't have kicked in THAT fast... The feeling is one of warmth in the body, primarily. There's no stimulation, and very little headspace. It's comfortable.

8:41 - The erotic was a fail. While I wasn't horny earlier, it doesn't take much for me, and I was really looking forward to an erotic night in. This material surprised me with a strangely unerotic headspace.
This material surprised me with a strangely unerotic headspace.
Unerotic, not totally anaphrodesiac like I find mushrooms to me, where sex sounds repellant or anathema. It's actually a bit like 4-AcO-EPT: very comfortable and a little self-contained. This is milder, though. I still felt affection, but absolutely no desire. Well, I felt some pretty strong desire for the pizza in the fridge, but not sex. I REALLY wanted pizza. Otherwise, I was mostly in a cerebral frame. Erection was possible, but never have I had to work this hard for it on a psychedelic.

It was a little like I've heard MDMA described, where intimacy was enjoyable, and while sex seemed like a fine way to express it, I just wasn't into it. I enjoyed touching and being touched, but it was just kind of fine. I respond idiosyncratically to MDMA, so if this shares a similar mechanism (say 5HT1a agonism?) that could be why. Also, this didn't make me feel noticeably more intimate, just a bit more open and a bit more disinhibited. I attempted orgasm on my own just to see if it was possible. It was, but it took some work and wasn't all that satisfying. The orgasm was weird--it was strong, but not impactful, resonating alongside the singing viola strings of my nervous system as they kept playing that placid chord of pleasant contentment.

Despite that, there is some tactile enhancement. I spontaneously noticed and enjoyed the sensation of walking barefoot on the floor, at least a little bit. Pulling clothes on gave me a few waves of cold shivers, too, but none of this played into eroticism.

My headache is manifesting more than at any other point today, but it hasn't been bothersome.

9:26 - Still starving, but somehow haven't gotten around to eating. I think this is an appetite enhancer, or maybe my hunger and libido switches got crossed (wouldn't be the first time.) I'm still at a solid ++.

Music isn't enhanced, though. I haven't noticed any OEVs, and CEVs are ludicrously faint and subtle, like a highly detailed shimmering gloss streamer across whatever phosphenes happen naturally. Basically absent. Side effects are absent, too. I could see muscle tension arising at higher doses, but nothing at this level. It does have a little of that gritty, grimey body feel that 5-MeO-MiPT has, but with less going on (like pleasurable body energies and tactile enhancement) to distract from it. It's fine, though.

Despite the relaxing nature and lack of stimulation, it might be hard to sleep? Tough to say. My pupils are finally substantially dilated. There's not really a lot more to say. It's pleasant and stoning. Maybe revisit with freebasing and vaporization?

9:40 - I still feel like I could go out in public at this level, especially to events where a little inebriation would be expected. It's hard to be sure, but I think it'd be pretty easy and not unpleasant. This has no hint of anxiety to it. It's also not one to leave me incapacitated and bored. I feel like I could read, game, surf the internet, watch movies, whatever right now without being all that debilitated. I'm not sure how long I would be entertained by just listening to music. I find it hard to do that as an activity anymore unless I've taken a psychedelic. While this wouldn't enhance my experience, it might reduce my racing mind and restless desire to do something else without coloring the music much if at all. This could be a nice booster psychedelic for other psychedelics based on it's clarity, positivity, and neutrality. A psychedelic salt, as I've heard 5-MeO-MET referred to. I'm not sure of the best ROA.

I do feel like the effects have been strengthening rather than subsiding, although they're still quite mild.

10 - Nope, effects started to taper down I think. Feeling sleepy. Chowing down on Cheezits.

10:30 - Effects have definitely started downswing. I'm still feeling them strongly, yet I feel like I could sleep. I am still quite hungry, with brief bits of horniness. Don't feel like I'd even need alcohol or a benzo or anything to sleep.

11:26 - Went to bed and fell asleep relatively easily. The body energy was still springy within me, feeling a lot like rubberbands or a trampoline membrane. Tense, but yielding. A higher dosage could have kept me up, I think. At this dosage, it seemed like the mental peace counteracted the body energy well enough to sleep within fifteen minutes.

Next day: Slept soundly and well, waking with a lot of the same feeling of relaxation and emotional contentedness. Honestly, as light and functional as the experience was, it was a lot like I was still experiencing effects.

Conclusion: Although I didn't get much out of this or see any immediate use, I could see myself exploring this material further. It's short duration, positivity, and total absence of side-effects makes it a low-commitment endeavor to explore to see if there's utility.

Did I enjoy it? Meh. It wasn't at all unpleasant, but apart from experiencing a change of consciousness I didn't get much out of it. I'm not one to smoke pot and watch Netflix, but that's where this seemed to fit in the taxonomy of experiences. I DID notice a quieting of internal dialog from a frenetic pace to one where it was more calm and deliberate.
I DID notice a quieting of internal dialog from a frenetic pace to one where it was more calm and deliberate.
This might be good for acute anxiety (apart from the come-up jitters.)

It defintely felt lighter and less serious than 5-MeO-MiPT, but I didn't see much resemblance at all to 4-HO/AcO-MiPT. My friend thinks of 4-HO-MiPT as 'super pot,' though--a connection I could definitely see being made with this material. For me, it was more like very subdued mix of the effects of 5-MeO-MiPT, 2C-B-Fly, and perhaps the emotional contentment of 4-AcO-EPT. I suppose I will revisit this orally in the future; I'd like to explore other ROAs, but the duration will likely be too short.

Like MDMA, I feel this material may need to be reclassified from psychedelic into a new, unknown category. From reading what the dozen or so published reports, it seems that no one has described any significant, classical psychedelic headspace shifts at any dosage or ROA. Massive increases in dosage seem to produce increases in intensity, but with no emergent psychedelia. So if not a psychedelic, what is it? And what can that tell us about structure activity relationships?

The bodyfeel:
Here's what it isn't. While it is mellowing, its action is not sedative like a depressant. While it is anxiolytic, it doesn't feel much like a benzodiazepine. While it is stoning, it doesn't feel particularly cognitively stultifying or blunting. While it is like a warm and comforting blanket, it doesn't feel much like an opiate. It really does feel like someone has decoupled the pleasant body energy and somatic sensations that pretty reliably accompany 5-MeO-MiPT, 2C-B-Fly, or 4-AcO-EPT from the rest of the spectrum of psychedelic experience. Psychedelics throw down the gauntlet, presenting the user with a challenge, an opportunity for growth. This does the opposite, blanketing the user firmly in positivity and contentment. I could see this being potentially useful to those wanting to work with deep materials that are notoriously either neutral or fickle, perhaps mushrooms or 2C-E. Combining them and adjusting the doses down for synergy *might* make them less intimidating without the clouding that benzodiazepines can cause. Still, this is unknown terrain. We know nothing about the possible health risks of combining this with other drugs. I've read only one combination report with a 4-substituted tryptamine, and it indicated that there was definite potentiation. I would love to see some ligand binding assays on this to see its affinities for 5HT2a vs 5HT1a, just to rule that out. Sasha might be right about this one - if it has similar ki values as 4-HO-MiPT, it could provide some great insight into structure activity relationships.

The mind:
This can be summed up succinctly. Thoughts quieted and racing thoughts stilled, focusing my inner monologue. There was a little bit of disinhibition. Anxiety diminished as a feeling of warm contentment grew within me, feeling strangely antidepressant. These effects lingered long into the following day. I would love to see neuroimaging studies on this material, particularly on brain region connectivity and default mode network activity. It would be interesting to see if this produces default mode network suppression or not based on its anti-anxiety/depressant effects. As some researchers have theorized that psychedelics produce their effect by increasing brain connectivity, it would be interesting to see if this non-psychedelic psychedelic produces connectivity comparable to its truly psychedelic analogs.

I look forward to a time where substances like this are used in functional selectivity studies, so that we can learn how different ligand structures produce the differences in signalling molecules that create such a wide variety of somatic, psychedelic, visual, or transpersonal effects.

Exp Year: 2018ExpID: 111805
Gender: Male 
Age at time of experience: 36
Published: Apr 10, 2018Views: 3,198
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4-MeO-MiPT (404) : Alone (16), Sex Discussion (14), Music Discussion (22), First Times (2), General (1)

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