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Handle With Care
Lyrica & Oxycodone
by ambrit
Citation:   ambrit. "Handle With Care: An Experience with Lyrica & Oxycodone (exp114404)". May 15, 2020.

25 mg oral Pharms - Pregabalin (daily)
  10 - 20 mg oral Oxycodone (daily)


My wife had her lower left leg amputated due to cancer. The doctors prescribed oxycodone and lyrica for bodily and specifically nerve damage pain. The Lyrica dose was 25mg twice a day with oxycodone 2.5mg eight times a day.

After a while, several weeks, the wife began to sleep for over half of the hours in the day. By two months after the surgery, dizziness and trouble with balance and motor control began to limit her mobility. (One leg is hard enough, but when you're that impaired, even a self driving wheelchair would be problematic.) So, to experiment, she cut the Lyrica down to 25 mg once a day, before bed time. The motor control issues faded away and she slept roughly normally. The pain was manageable. By the third month, the sleep issues returned. She decided to try stopping the Lyrica altogether. The sleep issues stopped.
She decided to try stopping the Lyrica altogether. The sleep issues stopped.

Now, at four months after the surgery, she has the oxycodone down to 2.5mg, five or six times a day. Her sleep is normal and the pain is manageable and lessening over time. Her assessment is that the Lyrica with the oxycodone displays a synergistic effect. I have swiped a few of the no longer used Lyricas to help with my occasional migraine headaches. It takes a half hour or so, but relief is supplied.

We both agree that the Lyrica is stronger than most people would suspect.

Exp Year: 2020ExpID: 114404
Gender: Female 
Age at time of experience: 76 
Published: May 15, 2020Views: 1,402
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Pharms - Pregabalin (418) : First Times (2), Hangover / Days After (46), Second Hand Report (42), Medical Use (47), Not Applicable (38)

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