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Extremely Lucid and Sharp
Bupropion, Pseudoephedrine & Caffeine
Citation:   TomDeQuincey. "Extremely Lucid and Sharp: An Experience with Bupropion, Pseudoephedrine & Caffeine (exp117941)". Erowid.org. Sep 8, 2025. erowid.org/exp/117941

 
DOSE:
T+ 0:00
300 mg oral Pharms - Bupropion
  T+ 1:00 180 mg oral Pseudoephedrine
  T+ 2:00 60 mg oral Pseudoephedrine
  T+ 2:00 200 mg oral Caffeine
BODY WEIGHT: 83 kg
I'm an experienced drug user, besides my addiction to opioids developed at 20yo.

One night I fell asleep very early and at 3:00AM woke up, and felt rested (7h slept) so I cannot continue to sleep and decided to experiment mainly with pseudoephedrine (I never used recreationally this drug, thinking that it may not had any valuable recreational/functional properties, I cannot were so wrong) that I bought the day earlier.

T-0:00 pseudoephedrine, being weaker than European speed/Adderall, I decided to potentiated with 300mg of Bupropion SR, and wait an hour before taking pseudo.

T+1h took 3 actifed (pseudoephedrine 60mg/each) for a total of 180mg. I looked online how long it takes to kick in and I saw a timespan of 30-90 min. I was on empty stomach.

T+1.5h start to feel a tingling sensation in my arms and head, definitely not a placebo effect.

T+2h maybe the bupropion is starting to kick in, I feel a very lucid and wakeful state of mind, before that I felt relaxed but not wakeful nor want to do stuff. I took another 60mg for a total of 240mg of pseudoephedrine and 200mg caffeine pill.

T+3.5h I feel awesome, the tingling sensation is a sign of the pseudoephedrine taking effect, I step up and go writing this experience on my whiteboard, to remember dosages and mainly to do something, cause I feel the need of playing videogames, read, write and even study!

The combination of the drugs and timing was perfect, I felt like this for another 2h before the effects starts to fade.

From that night I sometimes use pseudoephedrine, even alone, to fight lethargy or help study, more important, to fight that sensation of boringness due to my Major Depressive Disorder that knock my ass on the couch all day, well, with this drug I can do stuff normally, feeling better. It's not recommend taking it daily for tolerance, I take some break every 2-3 days. It's more a tool to be used than a mere drug for party, I want to experience in social context.

Exp Year: 2024ExpID: 117941
Gender: Male 
Age at time of experience: 33
Published: Sep 8, 2025Views: Not Supported
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Caffeine (11), Pharms - Bupropion (87), Pseudoephedrine (215) : Alone (16), Performance Enhancement (50), Combinations (3)

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Experience Reports are the writings and opinions of the authors who submit them. Some of the activities described are dangerous and/or illegal and none are recommended by Erowid Center.


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