DOSE:

200 mg

oral

6-APB

(powder / crystals)

BODY WEIGHT:

65 kg

This is an overview of 6-APB based on my multiple experiences on the drug.

Safety disclaimer:
6-APB is a triple reuptake inhibitor, and while it is considered to be less neurotoxic than MDMA (more cardiotoxic though), I treat it the same way and space out my use, while practicing proper harm reduction before, during and after ingestion, and aim for an overall healthy lifestyle to minimize negative effects and consequences.

Dosage:
I have bought many different (succinate) batches of this drug, and their potency varies quite considerably sometimes. I take around 200mg oral, as that dose has never felt too weak, nor too strong for me. I either do not redose (one dose lasts quite long already), or redose the same amount or slightly less 2 hours after the initial dose for prolonged, and somewhat intensified, effects.

Effects:
The effects are mainly comparable to MDMA, 6-APB is a very strong serotonin releasing empathogen, so it makes one feel amazing, love everyone, bond with anyone and feel energized. The main differences are that 6-APB is slightly more stimulating, very slightly less empathogenic (it is still very much an empathogen, but I have found that it doesn’t make me tell my whole life story to strangers the same degree as MDMA ), is a lot longer lasting and is slightly more trippy, being more closely related to MDA. This slight trippiness manifests in visuals resembling a low dose of LSD in somewhat higher doses, not in the headspace itself. I personally prefer 6-APB over MDMA in most cases, and it is an excellent party drug.

Timeline (without redose):
This is the description of an average 6-APB roll based on my experiences.

T-0:00: Ingestion of 200mg succinate.

T-0:30: By half an hour, I generally start feeling the first effects. Those being an elevated mood, increased talkativity, crisper vision and energy. The effects slowly build up over time, so do not make the mistake of thinking that you took too little and redosing before the 2 hour mark.

T-1:30-2:00: It is somewhere in this timeframe that the 6-APB fully kicks in; all the amazingness that MDMA provides, it is very similar.

T-4:00-5:00: Around this timeframe, the effects start subsiding, but instead of a big drop in energy and positive effects, it is a very slow decline. It is mostly the empathogenic effects that decrease, but the energy and amped up feeling remains. Even in this “comedown” phase, one is feeling quite nice and dancing still feels absolutely effortless.

T-8:00: at around 8 hours after ingestion, tiredness starts showing and one may feel like heading home from the party or at least sitting down. A good mood still remains though and the whole next day is characterized by an enjoyable afterglow. Sleeping is absolutely impossible after taking 6-APB unless with the help of benzos or taken early in the morning. At this point, appetite comes back, and it is very important to replenish energy and electrolytes with whole, healthy foods and paying attention to proper hydration (also during the roll ofc).

T-36:00: after the afterglow day is over and one had a good nights’ sleep, waking up with a slightly depressed mood is not uncommon. How severe it is will depend on the amount of drug consumed, how proper hydration was during and after, and how much attention was paid to recovery on the afterglow day. For me, this bad mood only lasts one day and after that I’m back to baseline, however some of my friends have suffered 2-3 days from it on occasion, so take that into account. On a sidenote, the severity of the comedown for me is less than that of MDMA.

Intranasal ROA:
The previous description was for the oral ROA, which is far superior to IN in my experience, however IN still has its place for certain occasions. If you are looking for a less entactogenic/more speedy and shorter experience, try IN. Doses are slightly lower and you can redose accordingly if you want to make it longer/stronger. Generally, one line will take about 20-30 minutes to reach full effects, peak for around 1-2 hours, and most effects are gone 5-6 hours after ingestion. Snorting 6-APB is nice, but oral is better and more efficient.

Combinations:
It is a strong drug and no enhancements are needed to enjoy its effects. Still, in this section, I describe the drugs that I have combined it with.

Alcohol:
A few times, I have taken it at festivals after being already drunk. This combination is not worth it. Once it kicks in, the alcohol effects are completely diminished, however drinking greatly exacerbates the comedown.

Weed:
The few times when I have smoked weed were after the peak was over, and were generally nice with increased visuals and somewhat increased positive effects. Weed can make me very confused if taken during a 6-APB roll.

Dissociatives:
I am an avid enjoyer of PCP analogues and sometimes I have snorted small amount during the roll. It greatly increases the positive effects and is very calming, while being energizing. I would not do this without extensive experience with these drugs, the combination can greatly increase the risk of mania. Confusion is also a concern with this combination.

Other serotonergic stimulants:
As a disclaimer first, combining serotonin releasing stimulants greatly increases neurotoxicity and the comedown, this way I do not recommend doing this. I have tried these combinations though, so here is my experience. The drugs used were 2-MMC, MDMA and 2/3-FEA (can be bought in a pellet form from certain RC vendors). When doing this, I took 1-2 doses of these drugs once the 6-APB was over, to have a prolonged peak without having to endlessly redose 6-APB. It works its purpose and I absolutely feel like I am constantly peaking for 8-10 hours, however as I have said, the risks are greatly increased this way, so proceed with caution (or not at all).

Exp Year: 2025	ExpID: 118801
Gender: Male
Age at time of experience: 23
Published: Jun 14, 2025	Views: Not Supported
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6-APB (516) : Combinations (3), Retrospective / Summary (11), Various (28)