DOSE: T+ 0:00	50 mg	oral	2'-oxo-PCPr	(capsule)
T+ 5:30		oral	Alcohol - Beer/Wine
T+ 6:30		oral	Alcohol - Beer/Wine

BODY WEIGHT:

210 lb

I have had the pleasure of being able to try the novel compound O-PCPr recently and was extremely surprised by what I experienced. After seeing this compound for sale and reading the report made by the great dissociative enthusiast nervewing, I had to follow in their footsteps to try this one and write out at least one report. The report from nervewing made this compound out to be less stimulating than O-PCE, but more stimulating than DCK, with seemingly no mania throughout the experience or afterglow. This was especially enticing to me, as I am predisposed to mania and specifically stay away from PCP analogs. I felt it was especially important to document my experience as I, unlike many dissociative users, prefer to take them orally. This led to an interesting surprise.

If you want to read about the chemical specifics of this substance, please check nervewing’s report, but I will state some basics. This is the N-propyl analog of O-PCE and DCK (O-PCM). It seems that 50mg of this substance is equal to 40mg of DCK, which matches with nervewing’s report. Due to this, my report will be on my attempt with 50mg of O-PCPr that I have built up to slowly with allergy tests. I do not have any noticeable dissociative tolerance, though I may have light tolerance from experiences with DXM, ketamine, 2-FDCK, 2-FXE, and memantine in the past with an average of 2-4 weeks between each. My test kits showed general results that match similar compounds like O-PCE and MXPr, but I would prefer somebody trustworthy and with better equipment to show exact test kit results and more precise information like NMR and GC-MS.

Now, I will set the scene for the day on which this was taken. I was ~210 pounds at the time of this experience. The day before, I had taken a 10mg oral dose of amphetamine sulfate and 2.2mL of 1,4-butanediol throughout the day. The night before, I took my nightly guanfacine ER 1mg dose, which I have been taking daily for months. I did not take any prescribed medications in the morning, something that had been true for 4 days prior to this experience. Usually, I take 200mg of lamotrigine daily in the morning. I did drink a coffee that contained approximately 90-100mg of caffeine, but I use caffeine daily at doses up to 700mg, so this was more to keep myself at baseline in line with my tolerance. My plans for the trip were to find an activity to settle into and not force anything, as I did not know what kinds of activities would be best to do on a more dissociative dose of this substance.

Now, at 6:38 P.M. on April 1st, 2025, the main event of the day is set to unfold. Some of these notes were written during the trip, while some were recorded in voice and video notes. All of it is transcribed here in order of actual events:

-5:17 – I drank one coffee with somewhere between 90-100 mg of caffeine. This is not important to the experience because of my tolerance and average daily dose of 200-300mg of caffeine.

+0:00 – I have weighed out approximately 50mg of O-PCPr into a vegetable capsule and taken it with a full glass of water. I am slightly tired from the lack of usual caffeine and current life events, but my excitement for the experience is keeping me awake.

+0:17 – I have noticed first signs of any bodily reaction to the O-PCPr. It feels as though I am getting light motion blur, though I can not tell whether this is placebo. What is real is the nausea and stomach pain that begins to emerge, which I tend to get with all oral dissociatives. It is not nearly as bad as 2-FDCK and 2-FXE and nowhere close to DXM in terms of these side effects. I hope that this is a sign that it is better for the stomach and possibly all internal organs than the less potent ACHs (ketamine/PCP analogs) I have tried.

+0:30 – As if it is purposeful, I am starting to notice effects right at the 30-minute mark. There are hallmark signs of dissociatives that are beginning to emerge, with buzzing in my extremities, a loss of feeling in my teeth, and the feeling of floating both physically and mentally. Visually, things are beginning to look fuzzy with a heavy layer of visual snow. These effects have all made it hard to continue the conversation I was having with my partner about cities in southeast China. It is also interesting to note that the nerve pain in my back has decreased more than with any other dissociative I have tried, and the peak has yet to even begin.

+0:35 – Only 5 minutes later, it is beginning to lay on a heavy and clean dissociation. The double vision is making it hard to see details of anything without closing an eye, and my perception of gravity feels like the ground is pushing up toward me. The feeling of separation from the parts of my body is stronger than I have gotten with most other dissociatives. Sounds are also beginning to sound as if they are further away and of lower quality.

+0:42 – I switch to using videos to log my notes at this point, as my ability to write is severely diminished by the mental disconnection and double vision. I move to my room to continue the trip, especially as my partner is about to call their brother, and my motor skills have diminished to the point of needing to hold onto walls to move. Colors are noticeably dull while maintaining their general hue, and any object that I am not mentally focused on loses all of its fine details. For objects that I am focused on, not actively taking in details causes those details to become static, and the height (but not width) of objects seems to expand. There is no noticeable effect on any senses other than sight and hearing, which has not changed in the last 7 minutes.

+0:55 – Seeing any object has become very difficult without extremely active focus on details, while closed eye visuals were only very vague, tall, skyscraper-like structures made of the colors I could see through my eyelids. My sense of touch has also become very disconnected, with my phone, my skin, the wall, and my bed all seeming to be the same texture. There is a strange hallucinatory taste of something bland like pasta water that almost seems to be the taste of a lack of taste. As for hearing, sounds seem to be vibrating in a way, almost as if they are being sent through a motorized toy fan. These are very clean disconnections with no hallucinations, something that is not true for other dissociatives like ketamine. This leads me to believe that this is a clean dissociative with hallucinogenic properties mostly or entirely at the NMDA receptor.

A decrease in my mental sharpness alongside my visual impairment has led to me taking \~7 minutes to write a single two-sentence message to a friend. My sense of self has diminished enough that my brain has set itself instead on analyzing the mechanics of other people and their interactions. This lack of mental sharpness and movement from my sense of self has seemingly made the concepts of ideas blend together, where something that I perceive about an idea or object gets applied by error to nearby or similar ideas or objects.

A strange and important note at this point is the lack of characteristics that I have found in other dissociatives. There is no feeling of bodily movement – no spinning, no sliding, and no perceived movement of a motionless object. There is also no brightening of the room like on 2-FXE or DXM, and no sedation like on ketamine or 2-FDCK.

+1:08 – The dissociation is already beginning to come down and put me back into a normal sensory space, though very gently. This is very strange for me, as the dissociation on even 2-FDCK does not fade as quickly as this, especially after waiting so long for the come-up. Up to this point, all sensory inputs, mental strain, and physical body load have felt heavy. The pain relief is starting to fade, and a light stimulation is starting to rise from the dissociation. As the similar compound O-PCE is a stimulating dissociative, I expected a light stimulation, so this is unsurprising for me.

+1:35 – Over the last half hour, only subtle changes have occurred. The dissociation is going away slowly, though most oral dissociatives seem to give me a quick come-up, short peak, and long come-down. However, this feels to me as if it was a longer come-up, similar short peak, and possibly shorter come-down than with 2-FDCK and 2-FXE. As O-PCPr is part of a set of notoriously slightly longer-lasting dissociatives, I find this very strange. It has also given rise to more stimulation than I’d have expected, putting it on par at the current moment with a typical therapeutic dose of methylphenidate. Either way, I am still dissociated enough to have motion blur and weird auditory effects.

+1:50 – The dissociative aspects are very low now, and yet the stimulating character is continuing to grow. This feels like a full dose of a reuptake inhibitor paired with a single bump of ketamine. It reminds me of how I have felt with oral 2-FXE in the past, where the dissociation would come down into hypomania that lasts around 2 hours. However, this feels like there is no mania or hypomania, just stimulation.

+2:10 – At this point, the dissociation is barely noticeable at all. There is also no hypomania or mania. However, I feel myself still rising to the peak of the stimulation. This makes me wonder when the stimulation will finally reach its peak and if it will last for much longer than the dissociative comedown. The stimulant effects that I am feeling are starting to gain the character of a mixture of 4F-MPH and 4-FMA, with some involuntary jaw movement, wide eyes, talkativeness, increased focus, and the need to move and do things. I have never tried cocaine, but it seems to match the effects that I have heard of from coke users.

+2:45 – The dissociation is seemingly completely gone by this point, and I am left entirely with a full and powerful stimulation that is reminiscent of both 4-FMA and reuptake inhibition. While the jaw movement and style of stimulation (the "euphoria snowball") reminds me heavily of triple reuptake inhibitors, feelings like an inner head tingle and some of the push to act are more reminiscent of triple releasers. If there is one thing that I can characterize about the class of this stimulant, it is that it is definitely not recreational. I am also feeling impulsive, but not in a way that I would classify as manic or even hypomanic. I jokingly make a point to my partner that this would be the replacement in the stimulant ban that people are looking for if it weren’t for the huge dissociative rush at the start and the fact that my experience could be subjectively different than others’.

+3:30 – it appears that some extremely small lingering dissociative effects may be left, but they have not impaired me from any action I have done for the past hour. I decide to use the recreational stimulation to hyperfocus on continuing my current reading of Invincible, which happens smoothly but with some distractions from the need to be constantly active. I am engaged in the story, but do not find myself gaining anything or feeling particularly boosted in mood in the ways typical of ketamine or DXM afterglow.

+4:15 – I feel the stimulation dull for about ten minutes, but then it comes back in another wave! It feels like this stimulation peak will never end, and it is especially unwelcome as I did not expect it and PsychonautWiki says that DCK would be halfway through the comedown at this point.

+5:00 – With my partner driving for safety, I head to the nearby convenience store to pick up a beer and some food. I decide on a mango IPA that I’ve enjoyed before, some cookie dough bites, and chicken bites. The stimulation has come down to a reasonable level that is maybe about halfway or less. If I had eaten anything more than lunch and a few small things earlier on in the day before the O-PCPr, I would likely be unable to stomach food at all, but my experience with stimulants has let me know when to ignore the lack of hunger and look for other signs that show that I need food.

+5:30 – The food is not amazing quality or very healthy, but I enjoy it anyway. At this point, I drink about half of the can of beer, which is 9.9% and 18.9 ounces. This makes it about 22.2 grams of alcohol.  

+6:00 – At right around 6 hours after ingesting the O-PCPr, the stimulation has finally subsided, and I am left slightly drunk and very tired.

+6:30 – I drink the rest of the can of beer, taking in another 22.2 grams of alcohol. This makes me extremely tired, so I get ready for bed almost immediately.

+9:00 – Due to after-effects of the stimulation, I did not end up sleeping until around 3:30 A.M.!

I am unsure what to take away from this substance. Should I consider an oral dose of O-PCPr to be more of a dissociative or a stimulant to myself? It is very strong in both regards, but with different peaks at different times. Based on nervewing’s report, it seems that this may be an exclusive effect from oral dosing, making it much closer to O-PCE in this way. However, while O-PCE is known for mania or at least hypomania, I did not get anything like that from this substance. I may also be the odd one out for having dissociation reduce so quickly with oral dosing. If that is the case, then others may experience its stimulation at the same time as its dissociation, or might not even experience the stimulation at all. Reactions to this one may be strange, so take caution.

If my own experience is accurate to the general experience with this substance, then I could see this being used in a handful of ways. First, it could potentially make for a therapeutic agent that disconnects you from yourself to show you a different perspective before throwing you back into yourself with the stimulation you need to talk through and work on the issues you saw. Second, it could make for a great experience for a full rave, where early dissociation would line up well with early sets and lower crowds while the later stimulation would line up with the 2-3 A.M. crowds and bass-heavy sets. Third, it could be used as a way for somebody who enjoys both stimulants and dissociatives to get pieces of both during the same experience and save on shorter-lasting substances like ketamine and especially cocaine.

Either way, I hope to see more of this substance and similar ones available in the future. This has been an absolute treat to try, though not quite as powerful and euphoric for me as DXM. I want to thank nervewing again for pointing this substance out.

Exp Year: 2025	ExpID: 118855
Gender: Not Specified
Age at time of experience: 22
Published: Dec 24, 2025	Views: Not Supported
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2'-oxo-PCPr (982) : First Times (2), Alone (16)