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Be Careful If Mixing Psych Meds With Speed
Sertraline & Methamphetamine
by furthur
Citation:   furthur. "Be Careful If Mixing Psych Meds With Speed: An Experience with Sertraline & Methamphetamine (exp37945)". Erowid.org. Aug 9, 2018. erowid.org/exp/37945

 
DOSE:
50 mg oral Pharms - Sertraline (daily)
    repeated   Methamphetamine (powder / crystals)


One Saturday morning as my girlfriend and I laid in bed pondering what to do with the day I jokingly said, 'Let's get high.' After a little more joking around I realized I really did want to get high - despite my promise to myself I would keep hard drugs for the summer and even then only once a month - I am an ex-speed addict. Anyhow, one thing led to another and we ended up acquiring about .3g of crystal. We had a pretty typical experience, got fairly spun, started packing up her apartment, and talked a million words a second.

The next day was pretty typical too. Pretty drained – popped a few Vicodin and just laid around. The last several days, however, have not been typical for my girlfriend. The difference between this recent drug indulgence and the million or so others we have had over the last two years is that we are now both on psych meds. I’m taking 20mg Strattera a day and she is taking 50mg Zoloft a day. I didn’t have any drug-drug interactions. She did – which she starting feeling Monday. She said she couldn’t get out of bed for work that morning, was vomiting, had a headache, muscle aches, and felt pretty spaced out.

Tuesday morning I called her to see how she was feeling to have the phone answered by what sounded like someone with Down’s syndrome. Her words were all slurred and she wasn’t able to hold a conversation. Every 10 seconds or so I would get no reply and have to ask repeatedly if she was still there before getting an answer. The little I was able to understand made me realize all the problems she had Monday, except for the vomiting, had gotten worse. I went to see her after work – to take her to vote, it was Election Day. She was still slurring her words a lot, when I got her out of bed she was fairly ataxiated, and her cognitive abilities were definitely not normal. She also told me how she was having problems remembering things – for example she called her mother three times that day to ask her the same thing – each time completely oblivious to the fact that she had even spoken to her mother already that day. This was all scaring the hell out of me, but from what I know about drugs (which is quite a bit, as I am a drug nerd) I was fairly certain that their wasn’t any permanent brain damage – it just seemed like all the extreme side-effects of the Zoloft were exponentially amplified.

The next day, Wednesday, I called her to see if she was feeling any better and she sounded more coherent and she told me most of the problems, including the dazed feeling, had diminished some. The memory problems, on the other hand, were getting worse.
The memory problems, on the other hand, were getting worse.
She said she woke up that morning to find a casserole made and sitting out on the counter – which she had no recollection of making and figured she must have woke up in the middle of the night and made it.

Today I called her and she told me that she again was missing pieces of her memory. She said that sometime between 4:00am and 8:00am she must have gone to the store and bought some milk and cereal because when she woke up at 8:00am that morning she found two gallons of milk and some cereal on the counter – with no recollection of how they got there. So today she called several doctors’ offices trying to get an appointment and the best response she could get was the head nurse conveying her message to her doctor who said, “Don’t do speed, keep taking the Zoloft, and make an appointment to see a Psychiatrist.” I told her to quit taking the Zoloft.

Later today my girlfriend called her boss to explain the situation to him – telling him everything besides that speed use was involved. He was very understanding and said that his wife had a similar reaction to Zoloft. Apparently, shortly after his wife started taking Zoloft, she just up and walked off for two days without telling anyone. Two days later he found his wife in the kitchen making dinner as if nothing had happened She had no recollection of anything out of the ordinary having happened. Their doctor told his wife to stop taking the Zoloft – but the side-effects did not go away for a week and he found his wife doing odd things like throwing apples at the walls – and when he questioned her about what she was doing his wife said she was playing darts. But apparently his wife’s symptoms went away after about a week so this gives me hope that if my girlfriend stops taking her Zoloft her memory will come back too.

I did the best I could to research Zoloft (or any SSRI) + methamphetamine interactions before we indulged last weekend. I found very little on the subject so I figured it would be okay – based on my knowledge of how the two drugs work biochemically – but I was obviously wrong. So please people be careful. I wrote this report so that this info might possibly keep someone else in a similar situation from making a similar mistake. Play safe. PLURR.

Exp Year: 2004ExpID: 37945
Gender: Female 
Age at time of experience: Not Given 
Published: Aug 9, 2018Views: 1,698
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Pharms - Sertraline (88) : Second Hand Report (42), Multi-Day Experience (13), Hangover / Days After (46), Medical Use (47), Health Problems (27), Retrospective / Summary (11), Small Group (2-9) (17)

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