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Bad Combination
Tramadol (with Acetaminophen), Diphenyhdramine & Fentanyl
by stiv
Citation:   stiv. "Bad Combination: An Experience with Tramadol (with Acetaminophen), Diphenyhdramine & Fentanyl (exp47062)". Erowid.org. Jul 18, 2006. erowid.org/exp/47062

1200 ug buccal Pharms - Fentanyl  
  75 mg oral Pharms - Tramadol (pill / tablet)
  650 mg oral Acetaminophen (pill / tablet)
  200 mg oral Diphenhydramine (pill / tablet)


I had a terrible experience by mixing diphenhydramine and ultrcet one evening which almost culminated ina trip to the hospital.

I had been using actiq all day, my drug of choice and when I ran out I realized I had a few ultracet's laying around. At about 8 p.m. I dropped the two ultracets and half an hour later decided to go to bed. Since I have a large tolerance to deppressant drugs I took four sleep eze -d tabs which is equal to 200 mg. of diphenyhdramine, my usual dose for insomnia. Approximately ten minutes after taking the antihistamines I knew I was in trouble. It started with a vague sense of paranoia, which I unsucessfully tried to shake off. I turned the lights out and tried to go to sleep but the combination of drugs actually left me highly stimulated. Soon my heart was racing. I could actually see my chest beating. I woke my wife, who was not too pleased after I admitted what I had done and she helped me get dressed to go to the emergency room since I was sure I was going to have a heart attack. I forced myself to vomit but didn't see any pills fragments, by this time it had been a good hour since I had ingested the diphenyhdramine.

After I puked I started to feel a little better and slowly my racing heart returned to normal. The whole incident probably lasted 2 hours but was the most frightening incident of my life.

Exp Year: 2005ExpID: 47062
Gender: Male 
Age at time of experience: Not Given 
Published: Jul 18, 2006Views: 16,238
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Pharms - Tramadol (149), Diphenhydramine (109) : Combinations (3), Small Group (2-9) (17)

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