Pain Relief Not Up To Expectations
Meperidine & Promethazine (Meprozine)
by Dale
Citation:   Dale. "Pain Relief Not Up To Expectations: An Experience with Meperidine & Promethazine (Meprozine) (exp63331)". Dec 30, 2015.

200 mg oral Pharms - Meperidine (pill / tablet)
  100 mg oral Pharms - Promethazine (pill / tablet)
In the middle of May, 2007, I had lower-back surgery (discectomy) and I was given Vicodin and Percocet for pain. A few days later, I contacted the doctor who conducted my surgery to report that the medication I was taking for post-operative pain wasn't helping. He wrote me for a medication called: Meprozine 50/25. This is a combination of Demerol/Meperidine(synthetic Opiate Analgesic) and Promethazine (anti-nausea).

Anyway, I started off taking the recommended dosage of 100mg (2x 50mg capsules). Realizing it wasn't even as strong as the other medication I was already taking, I decided that I'd up the dose at the next time I was due to take my medications. I popped four capsules (200mg) to see if I could actually feel better. Here is a timeline of this medication's affect at high levels:

15 Minutes After Oral Administration - Not too much that I can tell at the moment. Still in a lot of pain and I don't notice any euphoria.

25 Minutes After Oral Administration - I'm definitely feeling impaired. I'm experiencing a euphoric sensation. It's rather powerful but is accompanied by a slight dizziness and disorientation. I'm still awake and alive, able to see and hear everything appropriately. No hallucinations, either audible or visual.

45 Minutes After Oral Administration - It's gotta be either peaking by now or damn close. i have a tremendous head-buzz but it's not unenjoyable. It's like the euphoria and the head-buzz are the same thing, just very enhanced. My pain seems to be controlled somewhat which is definitely the best out of anything else I could be feeling.

1 Hour After Oral Administration - Feels like I'm coming down a bit. The head-buzz has almost disappeared and the back pain is picking up in intensity. Still enjoying some decent euphoria.

1 Hour, 30 Minutes After Oral Administration - I'm pretty sure that's about it. I'm not feeling anything other then pain. No head-buzz or euphoria. No headache or hangover feeling. Just back to what I was before I popped the medication.

In closing, this medication doesn't seem like something a doctor/surgeon should prescribe for someone straight out of surgery or for severe pain. I will probably never take it again. I'm not at all satisfied with anything it has to offer. Not sure why it was prescribed over hydrocodone and oxycodone.

Anyway, that's it.

Exp Year: 2007ExpID: 63331
Gender: Male 
Age at time of experience: Not Given
Published: Dec 30, 2015Views: 4,230
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Pharms - Promethazine (336), Pharms - Meperidine (408) : Unknown Context (20), Medical Use (47)

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