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Had a Seizure in the Office
Tramadol & Doxepin
by Belladonna
Citation:   Belladonna. "Had a Seizure in the Office: An Experience with Tramadol & Doxepin (exp67503)". Jan 19, 2008.

200 mg oral Pharms - Doxepin (daily)
  4 tablets oral Pharms - Tramadol (pill / tablet)


[Erowid Note: Unconfirmed Serious Injury Report. This report of a serious injury was submitted without verifiable details or contact information. Erowid is choosing to publish this report to invite public comment and to allow anyone who knows about this event to submit details that we can verify. Neither this report nor any report of a hospitalization should be considered reliable without details that can be verified through hospitals, police reports, family members, or news reports. If you have information about this incident or other experience resulting from the use of any psychoactive substance we cover, please contact sage at]

This is a warning NOT to mix Tramadol/Ultram with Tri-cyclic antidepressants such as Doxepin. I was prescribed Doxepin to help me sleep, was taking normal dosage, 1 capsule/day, and took 4 Ultram/tramadol that day before work.

About 2 hours later, I was on a telephone conference call and started feeling jittery, then suddenly my jaw just started opening and closing and I couldn't control it, I was stuttering into my conference call. I had to slam down the phone. Next thing I remember, I woke up to see a complete stranger staring into my face asking if I was OK. that stranger, about a minute later, turned out to be my best friend at work. Complete amnesia, temporarily. There were paramedics there and I was told I had a grand-mal seizure, right there in my cubicle. I remember nothing of it. I went to the hospital and gradually (within an hour) remembered what medicines I had taken to do this to me.

I will NEVER take a tri-cyclic again, and ultram maybe in very small doses.

Exp Year: 2007ExpID: 67503
Gender: Not Specified 
Age at time of experience: Not Given 
Published: Jan 19, 2008Views: 20,924
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Pharms - Doxepin (204), Pharms - Tramadol (149) : Health Problems (27), Combinations (3), Large Group (10+) (19)

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