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Using DMSO for Transdermal Administration
Citation:   Enesi/Xenonsion. "Using DMSO for Transdermal Administration: An Experience with DMT & DMSO (exp70238)". Sep 23, 2008.

50 mg transdermal DMT
The experiment-Evaluate DMT administration via DMSO application through the skin.

To start off, DMSO is a very unique chemical. It is a low toxicity commercial solvent that will dissolve a number of polar and non-polar substances. And has the unique ability to absorb directly through the skin, carrying with it other substances. You can learn more by an online search of course, I'll keep this brief.

So i acquired some 99.9% pure DMSO. And diluted it down to around 80%. This level has been found to work better then 99.9% pure. I started out with a low dose of freebase, 5mg dissolved into just a few drops of DMSO. Applied to the wrist, no effects noted.

Continued all the way to 75mg with no effects being felt. DMT dissolves very easily in DMSO. Also it irritates the skin quite a bit. Leaving a red rash, or a sore arm for the rest of the day. This seems to subside as you use DMSO more and more.

The freebase did not work at all, so I made some DMT in the salt form and applied 50mg dose to the skin on the forearm. Slight irritation was observed, but less so then the freebase. The only effects I felt were a slight increase in heartrate after about 5 min. This could have been caused by either the DMT, or just normal anxiety.

To conclude, DMT dissolved into DMSO (freebase or salt) does not appear to be an effective method for adminstering the substance.

Exp Year: 2008ExpID: 70238
Gender: Male 
Age at time of experience: Not Given
Published: Sep 23, 2008Views: 13,757
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DMT (18) : Unknown Context (20), Personal Preparation (45), Combinations (3), General (1)

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