Blocks Marijuana High
Bupropion & Cannabis
Citation:   David the Awesome. "Blocks Marijuana High: An Experience with Bupropion & Cannabis (exp76297)". Erowid.org. May 31, 2019. erowid.org/exp/76297

 
DOSE:
200 mg oral Pharms - Bupropion (daily)
    oral Cannabis  
BODY WEIGHT: 135 lb
I had a very interesting experience with the antidepressant Bupropion, otherwise known as Wellbutrin: It completely blocked the effects of marijuana for me.

My usual experience with cannabis is that, even in small amounts, it makes me extraordinarily high with unusual prophetic-spiritual overtones. My method of getting high is orally consuming the marijuana, because I have asthma.

Upon being on Bupropion for about a month, however, I noticed that when I ingested copious amounts of marijuana I did not get high at all. I felt almost nothing. There was no mental high, no body high, and no sense of being outside myself.

I would have written this effect off if it had happened only once, but on more than one occasion, I consumed about 3 times more than I needed to completely lose myself in a high. I felt nothing. (Yes, it was a BIG disappointment.)

I decided to do a little experiment, because of this. I decided to stop taking the Bupropion for a full 24 hours to get it out of my system, and then ingest weed. And what happened? I got amazingly high. :)

Through trial an error, I have discovered that with my particular neurochemistry, Bupropion with near complete effectiveness blocks the high-making effects of marijuana.

Needless to say I stopped taking the Bupropion. :)

Exp Year: 2008ExpID: 76297
Gender: Male 
Age at time of experience: Not Given
Published: May 31, 2019Views: 1,343
[ View PDF (to print) ] [ View LaTeX (for geeks) ] [ Swap Dark/Light ]
Pharms - Bupropion (87), Cannabis (1) : Combinations (3), Not Applicable (38)

COPYRIGHTS: All reports copyright Erowid.
No AI Training use allowed without written permission.
TERMS OF USE: By accessing this page, you agree not to download, analyze, distill, reuse, digest, or feed into any AI-type system the report data without first contacting Erowid Center and receiving written permission.

Experience Reports are the writings and opinions of the authors who submit them. Some of the activities described are dangerous and/or illegal and none are recommended by Erowid Center.


Experience Vaults Index Full List of Substances Search Submit Report User Settings About Main Psychoactive Vaults