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Unexpected Reaction to This Combination
Buprenorphine / Naloxone (Suboxone) & Pregabalin (Lyrica)
by hoot10
Citation:   hoot10. "Unexpected Reaction to This Combination: An Experience with Buprenorphine / Naloxone (Suboxone) & Pregabalin (Lyrica) (exp81772)". Erowid.org. Apr 28, 2021. erowid.org/exp/81772

 
DOSE:
T+ 0:00
300 mg oral Pharms - Pregabalin (capsule)
  T+ 0:05 1 mg IV Pharms - Buprenorphine  
  T+ 3:00 1 mg IV Pharms - Buprenorphine  

BODY WEIGHT: 68 kg


Finland Buprenorphine Use and Story of One Time

Here in Finland there is no more heroin available on the streets, in the last 5 years it has become very rare and of poor quality, no one uses heroin anymore, everyone uses Buprenorphine instead. This is strange phenomena, I have heard that same thing is going on in some other country also, but just one.

Buprenorphine here comes in few forms:
Subutex - 40-50 euros per 8mg
Suboxone - 25 euros per 8mg (also 2mg pills available)
Temgesic 0,2 and 0,4 pills, price unknown. I bought ten 0,2 for 20 euros two days ago.
Norspan patch in various strength - these are very weak and considered impotent among users.

Use here is almost always intravenous, rarely are the pills filtered. Users just put piece of the pill 1-2mg usually in the syringe and draw water in, shake and inject!

Especially Temgesic tablets are never filtered, they are very small and considered harmless, because small amount of fillers. When I bought the ten 0,2 Temgesic I just put 8 of them in syringe and drew in some mineral water, waited them to dissolve and mainlined.

Many users seek Boosters to take with their buprenorphine, for its weak-medium strength opioid and tolerant users rarely get any 'vibes' from it. Known boosters are anticholinergics Diphenhydramine, Dimenhydrinate, these are not available here. But if one can speak well, one might acquire Marzine (cyclizine) very powerful hallucinogenic booster, not very different from Dramamines mentioned earlier. Orphenadrine is also known, but rare booster. I must warn you, I once snorted half on Norgeseic orphenadrine pill and experienced severe pain for hours and excessive bleeding from nose! Never snort orphenadrine.

Superior booster is Pregabalin (Lyrica) It has become very common in last years in the street and sought after. Users say that it doubles the effects and causes pleasurable nod and dreams with buprenorphine.

I have observed my friends under this combination, they had poor coordination, slurred speech, they were on very slow vibes and generally numb and happy.

Last night I had the opportunity to test this combination myself:

T+0 Ingest 300mg Lyrica pregabalin capsule orally.
T+5min. Injected ~1mg Suboxone, when this is injected one has to wait 30-40 minutes for naloxone to wear off so buprenorphine can attach to receptors, there is some data that this route of administration gives more powerful experience as naloxone leaves receptors more 'sensitive and responsive', no references though.

T+60 I can feel the buprenorphine, but not the pregabalin.

T+90 I'm gettin very stimulated, effects are exactly opposite to what my friend experience. My motorics and coordination are improved. I start to clean up places like in mania or on speed.

T+3h Stimulated like 40mg of d-amphetamine, I inject ~1mg more Suboxone.

T+4h30min. Stimulated like amphetamines, but without overwhelming sexual urge that always gets me. Pregabalin seems to have actually lessened the effects of buprenorphine, rather than boosted them. I have taken ~2mg, but I feel like I have had only 0,5mg, moderately stimulated and in slightly hallucinogenic state.

T+5h went to restful blow CEVs in color, random events, people, scenarios, reminded me of smoking YOPO, CEVs were so intense that I almost got scared. Very vivid and real images. I went with them for about and hour and then fell asleep

Woke up in the morning and bought few beer with friend.I wasn't at baseline when I woke up, I had poor balance and general weirdness in my brain definitely from Lyrica.

I had unexpected reaction to this combination, effects are much better than those that my friends get and I'm definitely indulging into this combo again as soon as possible!

I was under no medications or other drugs during the experience except nicotine, I was in neutral mood, setting was my friends place, with familiar surroundings. Nothing special that could have influenced the experience.

Exp Year: 2009ExpID: 81772
Gender: Male 
Age at time of experience: 25 
Published: Apr 28, 2021Views: 273
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Pharms - Buprenorphine (265), Pharms - Pregabalin (418) : Not Applicable (38), Retrospective / Summary (11), Combinations (3)

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