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For Amphetamine Tolerance, Smoking Cessation
Memantine & Amphetamine
by lps
Citation:   lps. "For Amphetamine Tolerance, Smoking Cessation: An Experience with Memantine & Amphetamine (exp85730)". Erowid.org. Feb 24, 2011. erowid.org/exp/85730

 
DOSE:
30 mg oral Amphetamines (daily)
  20 mg oral Pharms - Memantine (daily)
BODY WEIGHT: 150 lb
I take 30 mg of dextroamphetamine daily for ADHD. I found that taking 20 mg of memantine (I started at 5 mg and slowly moved up) substantially reduced my tolerance to amphetamine. It does blunt the peak a little bit, but it also stretches out each dose so it lasts longer-- useful for ADHD, somewhat undesirable for recreational use. Over time my tolerance to amphetamine went down to about where it was 2-3 months or so after starting, which is pretty good.

Also, another weird side effect -- it made me quit smoking cigarettes. I didn't want to quit, and I still was addicted to nicotine for a few days and craved it, but still I didn't want to smoke, b/c smoking just made me feel horrible. Very effective, I had tried to quit before so many times -- this time I wasn't even trying, and it actually worked.

Exp Year: 2010ExpID: 85730
Gender: Male 
Age at time of experience: 28
Published: Feb 24, 2011Views: 16,067
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Pharms - Memantine (309) : Combinations (3), Therapeutic Intent or Outcome (49), Medical Use (47), Not Applicable (38)

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