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A Smooth Ride - But Illness Attacked Next Day
2C-I, Cannabis & Escitalopram (Lexapro)
by Supdawg
Citation:   Supdawg. "A Smooth Ride - But Illness Attacked Next Day: An Experience with 2C-I, Cannabis & Escitalopram (Lexapro) (exp88712)". Jan 14, 2011.

T+ 0:00
20 mg oral Pharms - Escitalopram  
  T+ 0:00 15 mg oral 2C-I (powder / crystals)
  T+ 0:15   smoked Cannabis  
  T+ 5:20 6 mg smoked 2C-I  


I am a 21 year-old male. I have smoked weed everyday for about six months and I have limited experience with Salvia Divinorum, 2C-I, mcat, and JWH-18.

It has been finals week here at University and as a result I have been pretty stressed. Still, tonight I was feeling good, it was early, and so spur of the moment I decided to pull out some of my 2c-I that I’d been saving. It was about 8PM, and given a come-up of roughly two hours, I knew it would be a perfect experience for a party I was going to later that night (around 11PM). My goal in consuming 2C-I this evening was to increase my “connection” with others at the party, and post-party to enjoy the visualizations and also pursue some introspection.

I should note at this point that I am currently diagnosed with depression and have been taking Lexapro (escitalopram) 20MG daily for about 7 months. I am very grateful for this drug – it has done wonders for my social and mental health. Lexapro is an SSRI, rather than an MAO inhibitor, thus I consider it totally okay to consume with 2c-I, and most tryptamines in general. I can confirm this both by personal experience and also from research done online.

The only side-effect escitilorpam seems to have on my experiences is that it mitigates the effects of hallucinogens. This is definitely true with 2C-I and also Salvia – I just don’t trip NEARLY as hard as my friends. Still, in no way do I recommend taking a larger dose of 2C-I to compensate; while the escitilopram reduces the mental effects, the physical effects such as heartrate increase and temperature irregulation are still present.

So, let’s begin my night. I am alone in my room. Put on a lot of soft-light and begin typing up a list of all the “blessings I have in my life.” I’ve found this technique to be a great way to prepare my mind to become and remain positive for the experience.

-4:00 – Consume my daily 20mg of Lexapro – usually I do it in the morning, today I do it with dinner.

0:00 – Consume approx. 15mg of 2C-I orally on an empty stomach. I say approximately because my scale is a little off. Substance came in a base of hydrochloride salt – a fluffy white powder with no scent. I simply put some on my finger, stuck on my tongue, and washed down with water. Slight chemical taste.

+0:15 – Smoke Cannabis sativa. I smoke weed every day throughout the day. My tolerance is so high I don’t really get very high anymore. In my experience, weed is a great tool to maintain control of my trip if things begin to go south.

+0:25 – I feel a slight alert from the 2C-I. Typical. Full ride won’t begin for another hour or so. Slight clenching of the jaw is apparent and will last all night.

+1:30 – Slight CEVs. I am listening to “Pachebel in the Garden” - classical music mixed with nature sounds. So soothing. Music, and this album in particular, are incredibly enjoyable while on 2C-I.

+2:00 – feeling a lot of empathy; thinking about my family and how much I love them. I’m mostly happy, but notice a slight bit of negative thoughts creeping in. I’m also bored. The experience so far has been mostly bland.

+2:15 – I go to a small house-party with some guys from my fraternity. I found myself to be very talkative, and the number of people (40+) was in no way overwhelming. No one knew I had consumed 2C-I except for two people I had told. I am having a lot of fun at the party – absolutely no alcohol for me, especially with this drug – though I step out two or three times during the evening to smoke weed with some friends. I am much more sociable than usual – the music is also STELLAR. I feel each thump of bass almost corresponds with my heartbeat.

+5:00 – I notice I have feelings of frustration and am not enjoying the party any longer. Additionally, I can sense the 2C-I wanting to take over although its effects are negligible while at the party. I walk home.

+5:10 – Walk into my room. BAM! I’m really feeling it all the sudden. I feel a sense of disconnectedness from my surroundings – my room feels oddly foreign. I lay in my closet in silence with the lights off. I see visuals in my periphery. Essentially, I’m falling into what feels like a sea of “demon babies.” I see a constant torrent of crying babies whose eyes are darkened out and whose mouths are gaping open. I do not find this frightening. I say to myself, “wow, so this is how my depression/anxiety is trying to manifest itself? Bring it on, let’s work through this.” I attempt to discover the roots of my anxiety, but this drug is not allowing for very much philosophical introspection. Disappointing, but as I am learning, to be expected.

+5:20 – At this point I realize the substance is not affecting me nearly to the extent it should be. I deem it safe and acceptable to mix about 6mg of 2C-I and a little bit of kief in my one-hitter. I choose this method because I have never tried it, and the effects come on much more quickly. I smoke it and it is an overbearing chemical taste. I feel like a damn junkie with the way this smoke tastes.

+5:23 – BAM! Hits me very quickly. Wow. The effects are so strong. After waiting five hours, I finally am having the ride I’m looking for. I walk to my bathroom and look in the mirror. My face is contorting itself into different shapes. My eyes are small and my nose and mouth are growing. I think to myself, “I resemble a rat.” I am not disturbed by what I see. I can also control it.

+5:35 – Realizing this trip will offer nothing to me in terms of self-reflection, I decide just to enjoy it. I lay in bed with Deadmau5 radio on Pandora playing. I tried some dubstep but found it too dark than I could handle. For a good 30 minutes I listen to music, enjoy CEVs - mostly patterns that look like they have been rendered mathematically; lots of greens, constantly contorting. I feel euphoric and perfect. I’m drifting in a world between sleep and wakefulness. Although I am awake, it feels like a dream almost to the point that I feel I can control what will happen next.

+6:10 – I decide to consume a shitload of chocolate my roommate gave me. Its delicious. I finish the chocolate by chugging about 32oz of water. What a great night! Kind of boring - the 2C-I wasn’t very strong this time - but for once I experienced absolutely no negative physical effects of the substance – it has been an easy-to-handle experience.

+15:00 – I wake up the next day and begin to go through my day. Around noon I notice very strong feelings of nauseau. Why? I don’t even think the 2C-I is in my system anymore. I think nothing of it til I am hit very strongly with a need to vomit. I vomit up a large amount of brown liquid – it smells like chocolate.

For the rest of the day I am vomiting up liquid and I have severe diarrhea. I have never experienced this before as a result of 2C-I, and can’t imagine 2C-I is the cause. Is it? Or is it the chocolate? Whatever it was, I spend the next 24 hours absolutely miserable and sick. In hindsight, I think it was food poisoning from the chocolate. The whole next day really put a damper on how I feel about my experience with 2C-I the day before.

2C-I is a great substance when used correctly. I find it constantly increases empathetic feelings, provides good visuals, and allows for a ride that is easy to control. Still, the next day’s illness makes me question whether the 2C-I is the culprit. I will definitely do it again as soon as I am can convince myself that I will have a positive experience – both during and AFTER the trip.

Exp Year: 2010ExpID: 88712
Gender: Male 
Age at time of experience: 21 
Published: Jan 14, 2011Views: 18,033
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Pharms - Escitalopram (304) : Combinations (3), Depression (15), General (1), Various (28)

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