Modern humans must learn how to relate to psychoactives
responsibly, treating them with respect and awareness,
working to minimize harms and maximize benefits, and
integrating use into a healthy, enjoyable, and productive life.
SSRIs, SNRIs Block Its Effects
MDAI & Venlafaxine
Citation:   Rocketman. "SSRIs, SNRIs Block Its Effects: An Experience with MDAI & Venlafaxine (exp90884)". Erowid.org. Aug 11, 2011. erowid.org/exp/90884

 
DOSE:
T+ 0:00
200 mg oral Pharms - Venlafaxine (daily)
  T+ 0:00 100 mg oral MDAI (powder / crystals)
  T+ 1:00 100 mg oral MDAI (powder / crystals)
BODY WEIGHT: 150 lb
I have been on Effexor generic 100mg 2x a day for two months. The 2C family of drugs work fine. I can trip and do not need to miss a dose of my antidepressants. Methylone does not work very well, leaving me feeling physically warm and perhaps anxious, but nothing more.

Tonight I decided to try MDAI. Surprisingly there was no literature on combining MDAI with antidepressants. In my experience, SSRIs and SNRIs severely block the effects of MDAI.

I took 100mg, waited an hour and took 100mg. It is now 5 hours later and I can confirm that I had zero effects. It's as if I had taken nothing at all. I had tried this MDAI batch before and had excellent experiences on 100-200mg.

MDAI works like MDMA and so it is safe to assume that most of the effects are being blocked by the SSRIs/SNRIs. Perhaps a higher dose (300mg+) would be sufficient but may not be worth the money.

Again: Antidepressants that act as SSRIs or SNRIs will dampen my experience very much.

Exp Year: 2010ExpID: 90884
Gender: Male 
Age at time of experience: 25
Published: Aug 11, 2011Views: 9,210
[ View PDF (to print) ] [ View LaTeX (for geeks) ] [ Swap Dark/Light ]
Pharms - Venlafaxine (191), MDAI (499) : Medical Use (47), Combinations (3), Alone (16)

COPYRIGHTS: All reports copyright Erowid.
No AI Training use allowed without written permission.
TERMS OF USE: By accessing this page, you agree not to download, analyze, distill, reuse, digest, or feed into any AI-type system the report data without first contacting Erowid Center and receiving written permission.

Experience Reports are the writings and opinions of the authors who submit them. Some of the activities described are dangerous and/or illegal and none are recommended by Erowid Center.


Experience Vaults Index Full List of Substances Search Submit Report User Settings About Main Psychoactive Vaults