Citation: Pothedd. "Seems to Cause Seizures: An Experience with Unknown (MN-001, presumed UR-144) (exp94395)". Erowid.org. Aug 17, 2015. erowid.org/exp/94395
||(powder / crystals)
Received packaging that was quite... uh.. creative. It was a baggy, wrapped in paper, wrapped in duct tape, wrapped in paper, and this outermost layer was some kind of Czech dude-porn or some shit Idk. Hilarious, but no labeling. No idea what substance I had received, as I'd been waiting on more than one package.
Administered small dose intranasally, assuming it was ethylphenidate. Little reaction was noted, and the substance seemed less than soluble. Not ethylphenidate.
One vaporized hit produced signs of anxiety for an extended period, followed by depression. Subject recovered within a couple hours. A second dose produced the same response. The product melts and vaporizes freely.
After being told this was UR-144 I can see the reason behind the reaction. Far too much CB2 activity and not enough CB1. All anxiety, no euphoria. I wouldn't recommend anyone else test this substance.
Update: Another test run today, at roughly twice the dosage, caused violent seizures of the extremities. These subsided within thirty minutes, though the subject was completely aware of what was happening. Walking seemed to partially alleviate the symptom, though not fully.
This reaction has been caused in the past by one other substance, and was treated with benzodiazepines, but none were available this day.
CB1 receptors have apparent anti-convulsive potential, but I am not fully aware of the complex interaction between cannabinoid inverse/agonists/antagonists, the CB1 & 2 receptors, and non-CB1 or 2 receptors. This particular substance seems to CAUSE seizures, with little benefit for any other purpose.
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