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Alprazolam (Xanax) Health Concerns
by Erowid

* Every individual reacts differently to every substance.
* Be mindful at every step.
* Know your body. Know your mind. Know your source.

Contraindications (from the PDR):
Xanax tablets are contraindicated in patients with known sensitivity to this drug or other benzodiazepines. Xanax may be used in patients with open angle glaucoma who are receiviing approprioate therapy, but is contraindicated in patients with acute narrow antle glaucoma.

Xanax is contraindicated with ketoconazole anditraconozole, since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP 3A)

Dependence and withdrawal reactions, including seizures