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Diphenhydramine
Bits & Pieces
by Erowid

The "Bits & Pieces" section is intended for random snippets of information which don't fit
easily elsewhere and/or which have been newly added, but not yet carefully categorized.


  • Acetaminophen Health Warning
    Some young or desperate users looking to try diphenhydramine might pick up a product (such as Benadryl Cold) that contains a combination of medicines, including acetaminophen. Products containing acetaminophen should NEVER be used recreationally, even once. The dosages of products necessary for recreational use will deliver a potentially liver-damaging amount of acetaminophen. Especially in combination with alcohol, with repeated doses, in combination with other drugs, or in sensitive people, acetaminophen can lead to permanent liver damage, liver disease, or even death.

  • Dimenhydrinate and Diphenhydramine
    Dimenhydrinate is the 8-chlorotheophyllinate salt of diphenhydramine. The effects of both compounds are due to the same active principle, with one of the major differences between the two substance being dosage (50 mg of dimenhydrinate is equivalent to approximately 25 mg of diphenhydramine hydrochloride).