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Diphenhydramine (Benadryl)
Interactions
by Erowid
SUMMARY #
Listed below are some of the known interactions between Diphenhydramine and other chemicals, plants or pharmaceutical medications. This is not a comprehensive list.

POSSIBLE DRUG INTERACTIONS SUMMARY
Diphenhydramine
SUBSTANCETYPEDESCRIPTIONSYMPTOMSCONFIDENCEREFS
Opiates Increased Effects Erowid experience report of a person who experienced an increase in the euphoriant effects of oxycodone (IV) when combined with diphenhydramine (IV). euphoria, anxiolytic Tentative
Exp Report
Erowid 2008
If you have a positive or negative drug interaction to report, please let us know! Submit an interaction.
CAUTION & DISCLAIMER #
Erowid's interactions information is a summary of data gathered from first hand reports, research, and other resources. This page is intended to collect drug-drug and biology-drug interactions and is not exhaustive: other dangerous or medically important interactions may exist that are not listed here. Drug effects may vary dramatically from one person to another and from one experience to another based on a variety of factors such as body chemistry, age, gender, physical health, dose, and form of material.

REFERENCES #
  1. Anonymous. Experience 75597: Cranky to Blissful in 60 Seconds. Erowid Experience Vaults. 2008. erowid.org/experiences/exp.php?ID=75597