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Oxycodone (Percocet, Oxycontin)
by Erowid
Caution :   Reactions and experiences may vary dramatically from person to person. [see below]
Oxycodone Duration
Total Duration
3 - 6 hrs
10 - 30 mins
Coming Up
30 - 60 mins
2 - 4 hrs
Coming Down
30 - 60 mins
  • analgesia, reduction of pain (common)
  • sedation, sleepiness (common)
  • anxiolysis, reduction of anxiety (less common)
  • euphoria, mood improvement (less common)
  • feelings of relaxation (less common)
  • pupil constriction
  • sweating (common)
  • slowed reaction time (common)
  • changes in focus, attention, and thought (common)
  • impaired thinking, confusion (less common)
  • loss of appetite (less common)
  • hiccups (uncommon)
  • changes in vision (uncommon)
  • constipation (common)
  • nausea, vomiting (common)
  • dizziness, headache (common)
  • itching/pruritus (common)
  • dry mouth (common)
  • hyperalgesia, increased sensitivity to pain (rebound pain) (usually after stopping use)
  • fatigue, weakness (common)
  • nervousness (less common)
  • sleeplessness/insomnia (less common)
  • fever (less common)
  • diarrhea (usually after stopping use, 'rebound diarrhea') (less common)
  • difficulty urinating (less common)
  • clammy skin (less common)
  • light-headedness, fainting (less common)
  • acute withdrawal symptoms if physically dependent
  • decreased interest in sex (with habitual use)
  • abdominal pain (uncommon)
  • rash (uncommon)
  • seizures, convulsions (uncommon)
  • difficulty breathing (uncommon)
  • respiratory depression, respiratory arrest (uncommon)
  • tinnitus (very uncommon)
  • circulatory depression, shock (very uncommon)
Some adverse effects may be alleviated by lying down. Nausea, vomiting and other concerning effects may increase as dose increases.

Oxycodone is a semi-synthetic opioid analgesic used to treat moderate to severe pain. It is most effective treating acute pain rather than chronic pain. The precise mechanism of action of oxycodone and other opiates is not known, although it is believed to relate to the existence of opiate receptors in the central nervous system.

Erowid's effects information is a summary of data gathered from users, research, and other resources. This information is intended to describe the range of effects people report experiencing. Effects may vary dramatically from one person to another or one experience to another based on a variety of factors such as body chemistry, age, gender, physical health, dose, form of material, etc.