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Tramadol (Ultram) Health Concerns
by Erowid

* Every individual reacts differently to every substance.
* Be mindful at every step.
* Know your body. Know your mind. Know your source.

Drug Interactions:
There are case reports of people having bad reactions when mixing tramadol with SSRIs. This may include potentially life-threatening adverse reactions such as serotonin syndrome. (Australian Adverse Drug Reactions Bulletin 20:4 Dec 2001)

Tramadol has been associated with seizure activity, especially when taken at high doses, when taken for multiple days in a row, and in combination with other pharmaceuticals. [Reference, RXlist Warning, Medical Journal of Australia]

References #
  • Australian Adverse Drug Reactions Bulletin. Volume 20, Number 4, December 2001