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Salvia Extraction
Denatured Alcohol

See also : Water then Acetone Extraction
See also : Isopropanol or Reagent Grade Acetone

Denatured Alcohol :

  1. Take approximately 30 dried leaves and crush them by hand.
  2. Put them in a mason jar soaking in 1/2 cup of denatured alcohol.
  3. Let soak for 2 hours.
  4. Decant (pour off) the alcohol into a small non-aluminum dish.
  5. Add about 5 dried crushed leaves.
  6. Set a fan to blow over the dish to speed the evaporation process.
  7. Preheat oven to 250 degrees F.
  8. Turn oven off and place dish inside the oven while it's still hot.
  9. The small amount of water absorbed by the alcohol should dry within about 15 minutes.
  10. Scrape all material from the dish with a razor blade (that's why you're not using an aluminum dish).
  11. Smoke with care.
In this method, the denatured alcohol (pure ethanol with a small amount of methanol added) seems a good alternative solvent to acetone as Valdez reported using aqueous methanol as a polar solvent to extract nonpolar hexane extracts, increasing the concentrations of salvinorin-a before using chromotographic separation to obtain the purified compound.