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Sacchi U, Brusa A, Soriani S. 
“Alterazioni istologiche del sistema nervosa centrale provocate sperimentalmente nel topo da trattamento cronico con 5-idrossitriptamina. Azione protettrice dell'LSD somministrata preventivamente.”. 
Sistema nerv.. 1957;9:230.
Serotonin caused pronounced histological changes in the brain and spinal cord of white mice when administered i.m. for 20-30 days in increasing daily doses (0.33-2 mg.). The histological changes were much less pronounced, if 0.25 mg. LSD was injected 20 minutes before the serotonin. . These histological investigations show that LSD protects the nervous tissues against the effects of chronic serotonin intoxication.
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