Plants - Drugs Mind - Spirit Freedom - Law Arts - Culture Library  
Erowid References Database
Melander B, Martens S. 
“The mode of action of taraxein and LSD.”. 
Dis. Nerv. Syst.. 1958;19:478.
Taraxein (isolated from 400 ml schizophrenic serum) given i.v. to monkeys induced withdrawal with catatonic features. 2-3 mg/kg Kabi 888 [a phenothiazine derivative?] given i.v. at the peak of the taraxein effect caused immediate loss of muscle tone, piloerection and deep sleep. . LSD (15 mcg/kg) given i.v. to monkeys caused slight withdrawal and catatonia. 2-3 mg/kg Kabi 888 given i.v. after LSD caused loss of muscle tone and a sleep-like state. . Adrenolutin (20-25 mg/kg i.v.) had only a slight effect in cats and monkeys. If the animals were pre-treated with LSD or taraxein, as little as 2-3 mg/kg adrenolutin produced drowsiness and muscular relaxation. . Acetylcholine, epinephrine, and adrenolutin, atropine, mescaline, and 5-hydroxytryptamine given i.v. to cats had little or no effect. When given after LSD, they exerted the same striking effects as seen after intraventricular administration. . Preliminary studies were made of ALD 52 and BOL 148. The effects exerted by LSD were also exerted by ALD 52 but not by BOL 148.
Comments and Responses to this Article
Submit Comment
[ Cite HTML ]