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Monnier M. 
“Stimulants hallucinogènes, psychotoniques et analeptiques du système nerveux central.”. 
XXIst International Congress of Physiological Sciences, Buenos Aires, Symposia and special lectures. 1959 August;p149-158.
Analysis of the effects in animals - especially using electroencephalographic criteria - of hallucinogens (e.g. LSD, mescaline), psychotonics (e.g. amphetamine) and analeptics (e.g. metrazol, coramine etc.). This yielded the following characteristics for LSD. . Behavior and vegetative tone: stimulation in the ergotropic sense. Sensory receptors, pathways and centres: Activation of the retinoelectrogram, enhancement of the synaptic transmission in the lateral geniculate body by small doses, inhibition by higher doses; inhibition of the occipital cortical potentials elicited by optic or electric stimuli of the optic tracts. . Spontaneous cortical EEG: desynchronization in the neocortex, synchronization in the paleocortex (hippocampus). . Arousal reaction by sensory stimulation or the stimulation of the reticular formation: increased (Psilocybin has only a minor influence on the reticular formation). . Recruiting effect of stimulation of median thalamic nuclei: inhibited. Formation of spikes in the paleocortex: increased. Transcallosal corticocortical conduction: inhibited. . Especially characteristic for the effect of LSD and other stimulants is the enhancement of the arousal reaction due to stimulation of the reticular formation and the simultaneous inhibition of medio-thalamic "recruiting", further the desynchronization in the neocortex and synchronization in the cortex.
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