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Hofmann A. 
“Rapport sur une auto-expérience avec le Psilocybe mexicana Heim”. 
Les champignons hallucinogènes du Mexique. 1958;p278-280.
Ingestion of 32 dried specimens of the mushroom Psilocybe mexicana Heim elicited physical and phychical symptoms analogous to those observed by Heim after ingestion of the fresh mushrooms. This personal experiment by Hofmann, therefore, indicates "that the active principle is preserved on drying the Psilocybe mushrooms and that the fractions obtained on extracting the dry mushrooms with chemical agents can be tested without danger on man". . In further experiments, a test was developed by means of which extracts containing the active substance can be differentiated from inactive extracts. This human test was the starting point in the isolation of the pure active principle in crystalline form - a substance which was given the name Psilocybin.
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