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Christiansen A, Baum R, Witt PN. 
“Changes in spider webs brought about by mescaline, psilocybin and an increase in body weight”. 
J. Pharmacol. Exp. Ther.. 1962;136:31-37.
[First Paragraph, no abstract -- Erowid]

Reports on the effects of mescaline (Beringer 1927; La Barr, 1938) and psilocybin (Heim and Wasson, 1958; Isbell, 1959) suggest that the two drugs affect man in a similar way. Both cause changes in pulse rate and respiration, a sensation of heaviness and discomfort, perceptual distortions (especially visual) and hallucinations. Isbell (1959) points out that methods of measurements and the situation in which human experiments are conducted may contribute in some degree to this similarity. The test method which uses the effect of drugs on spiders' web-building behavior can discern between the actions of a number of similar drugs (Witt, 1956). It appeared therefore an appropriate method for the detection of possible differences in the effects of mescaline and psilocybin.
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