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Savage C, McCabe OL. 
“Residential psychedelic (LSD) therapy for the narcotic addict. A controlled Study.”. 
Arch,Gen,Psychiat.. 1973;28(6):808-14.
Residential Psychedelic (LSD) Therapy for the Narcotic Addict. A Controlled Study. The efficacy of LSD-assisted psychotherapy in the treatment of heroin addiction was studied in 78 residential, male addicts. Methods All subjects (average age 28.6 ye) were heroin addicts resi-dent in an aftercare clinic for narcotic addicts. patients were randomly assigned to treatment or control (an,outpatient clinic programme) groups, and were then given 24 hr psychotherapy over a 5-wk-period. Subjects in LSD group were then given a single high dose of LSD (300-450 mcg) and experience monitored over a 12-hr period. All subjects then received a further wk of therapy designed to integrate experience into psychotherapy. Narcortic abstinence was monitored by daily urinalysis, and efficacy assessed by standard global adjustment rating scales. 37 Patients from each group completed the trial. Major outcome criteria were assessed in the 12 mth following discharge. Results Abstinence data based on urinalysis and follow-up during first post-treatment yr suggest that LSD-asissted psychotherapy can improve post-treatment abstinence. Total abstinence was reported in 9 of LSD-treated subjects, and 2 of the non-treated subjects. Another 3 treated-subjects relapsed briefly, and then remained abstinent for the rest of the yr. Evaluation by global adjustment rating suggested a more favorable outcome in LSD treated group. The results indicate that LSD treatment, under the conditions described, may assist in the rehabilitation of chronic heroin addicts.
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