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Vasko MR, Lutz MP, Domino EF. 
“Structure Activity Relations of some Indolealkylamines in Comparison to Phenethylamines on Motor Activity and Acquisition of Avoidance Behavior”. 
Psychopharmacologia (Berl). 1974;36:49-58.
The structure-activity relationships (SAR) of various known hallucinogenic and nonhallucinogonic indolealkylamine and phenethylamine derivatives were compared on two different behaviors: mouse locomotor activity and acquisition of one-way avoidance behavior in the rat. Certain parallels were observed between the two classes of compounds. a-Methyl substituted derivatives of the indoles and phenethylamines increased dramatically psychomotor stimulant effects. Acquisition of one-way avoidance behavior was reduced by the more potent hallucinogens and psychomotor stimulants of both classes. Pargyline pretreatment enhanced the psychomotor stimulant effects of all of the compounds tested except 5-hydroxytryptamine (5-HT), d-amphetamine, mescaline and lysergic acid diethylamide
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