Plants - Drugs Mind - Spirit Freedom - Law Arts - Culture Library  
Erowid References Database
Holbrook L, Brown IR. 
“Disaggregation of brain polysomes after administration of d-lysergic acid diethylamide (LSD) in vivo”. 
Journal of Neurochemistry. 1976;27:77-82.
Polysomes from three major brain regions of the young rabbit were disaggregated after in vivo administration of d-LSD. The effect was transient and demonstrated maximal shift after 30-60 min with a return to normal levels by 4 h. Brain polysome disaggregation was elicited by LSD dosages of either 10 or 100 mcg/kg body wt. The polysome shift was not caused by RNase degradation and during maximal disaggregation there was a measurable decrease in protein synthesis.
Comments and Responses to this Article
Submit Comment
[ Cite HTML ]