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Pickworth WB, Sharpe LG, Martin WR. 
“Transcallosally Evoked Potentials And the EEG In The Decerebrate Dog: Actions Of Tryptaminergic, Dopaminergic And Adrenergic Agonists”. 
Electroencephalogram Clin. Neurophysiol.. 1977;42:809-816.
Curtis and Bard (1939) electrically stimulated the cortex in the monkey and evoked a biphasic wave in specific areas of the contralateral cortex. Curtis (1940a) described the transcallosally evoked potential (TEP) as a wave having a surface positive component followed by a longer lasting surface negative component. The TEP was abolished by sectioning the corpus callosum. Curtis (1940b) proposed that the surface positive component was due to afferent activity in the callosal fibers, whereas the negative component represensed postsynaptic depolarization of interneurones. Although this interpretation has been challenged by Peacock (1957) and Grafstein (1959), the TEP has been used extensively by Marrazzi (1953, 1957) to study the activity of putative neurotransmitters:and hallucinogens on cortical synaptic activity. In previous studies in this laboratory, tryptamine, LSD-like hallucinogens and adrenergic agonists facilitated spinal reflexes in the chronic spinal dog (Martin and Eades, 1970) and in the acute decerebrate spinal cat (Vaupel and Martin 1971; Bell and Martin 1974). It has been proposed that the LSD-like hallucinogens act at tryptaminergic receptors to produce these facilitatory effects (Martin and Eades 1972). Kay et al. (1973) reported that tryptamine and LSD caused similar EEG changes in the encephale isole cat. The observations by Martin et al. (1975a, 1976) that both the cerebral cortex and the corpus callosum contained tryptamine stimulated the present study on spontaneous and evoked cortical activity. The TEP seemed to be a relevant model for the study of the effects of tryptamine, LSD-like hallucinogens and adrenergic agonists on the EEG and cortical processes in volving long interhemispheric axons.
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