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Denson R. 
“Dissociative delirium after treatment with lysergide”. 
Canadian Medical Association Journal. 1967;97:1222-24.
The adverse effects of hallucinogenic drugs constitute a topic which has given rise the major differences of opinion among psychiatrists and to numerous contradictory statements in the literature. Some authors have reported that unfavourable reactions are rare and ordinarily trivial, if the treatment is supervised by a physician who has acquired skill and experience in this particular field. Others have stressed the hazardous nature and frequency of the after effects, which they regard as a major barrier to the therapeutic application of these substances. Whatever view one adopts in this controversy, it must be conceded that the variety of adverse reactions attributed to lysergide is truly remarkable. To date these include homicide, suicide, attempted suicide, ecstasy with suicidal impulses, status epilepticus, acute schizophrenic reactions, severe depressions, anxiety, paranoid psychoses, prolonged hallucinosis, transiet recurrences of psychedelic phenomena, headaches, aggravation of pre-existing psychoses, and the production of a state of reverie and idleness and of 'a drug-addicted sociopathic individual. In this paper we descibe the development of recurrent episodes of dissociation in a patient who had taken lysergide some weeks before. This complication has not been reported in that portion of the literature on hallucinogenic drugs which has come to our attention and it has occurred in only one of the 260 patients whom we have treated with this compound.
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