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Ray OS, Bivens LW. 
“Performance as a function of drug, dose, and level of training”. 
Psychopharmacologia Berl. 1966;10:103-109.
Chlorpromazine CPZ at 1.0, 2.0 and 3.0 mg/kg and LSD-25 at 0.05, 0.10, and 0.15 mg/kg were administered to Ss given varying amounts of training on a discrete trial conditioned approach procedure. Both CPZ and LSD-25 showed significant dose-response effects, i.e., as dose increased, degree of behavioral depression increased. There was no relationship between the LSD-25 induced depression and the amount of training but CPZ showed significantly less effect on highly trained behavior than on moderately or minimally trained behavior.
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