Erowid.org: Erowid Reference 460 : MDL72222, a serotonin 5-HT3 receptor antagonist, blocks MDMA's ability to establish a conditioned place preference : Bilsky EJ, Reid LD

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Bilsky EJ, Reid LD. “MDL72222, a serotonin 5-HT3 receptor antagonist, blocks MDMA's ability to establish a conditioned place preference”. Pharmacol Biochem Behav. 1991;39(2):509-12. <a name="ref">Bilsky EJ, Reid LD.</a> <a href="/references/460">"MDL72222, a serotonin 5-HT3 receptor antagonist, blocks MDMA's ability to establish a conditioned place preference"</a> <i>Pharmacol Biochem Behav</i>. 1991;39(2):509-12.
Text Abstract (this page) Full Text - English (private) Show Articles by Bilsky EJ Reid LD Article IDs Erowid RefID: 460 PubMedID: unknown Collections Hofmann Collection MDMA Collection All References	Abstract Methylenedioxymethamphetamine (MDMA) has previously been shown to produce a positive conditioned place preference (CPP) among rats. Here the effects of doses of a specific 5-HT3 antagonist, MDL72222, on MDMA's ability to produce a CPP were assessed. A dose of MDL72222 (0.03 mg/kg) blocked the establishment of a MDMA CPP. These results support the suggestions that compounds affecting the 5-HT3 receptor may be of particular interest in studying the pharmacology of self-administered drugs.
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