Erowid References Database
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Garcia-Austt E.
“Effects of Psychoparmacologic Drugs upon Sensory Inflow in Normal Subjects in Psychiatric Patients and in Animals”.
Military Report. 1966;2.
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Abstract
A military report, exact publication unknown.
Marked as: AD-643 985 Fld. 6/15, 6/5.
Another source notes as: AD-852686
Descriptors: (*Psychotropic agents, Visual Perception), Vision, Humans, Animals, Responses, Stimulation, Chlorpromazine, Sleep, Lysergic acids, Electroencephalography.
Averaged visual evoked potentials are being studied in mand and animals by means of a computer of average transients (CAT). Modification incorporated to this computer are described. Effects of psychotropic drugs upon the averaged visual evoked response (VER) in normal subjects are studied. LSD 25 determined multiplication of the waves. The response amplitude increased during continuous flicker stimulation instead of decreasing as observed in controls. Chlorpromazine reduced VER amplitude both in wakefulness and sleep. Stupour and coma VER was simple, lower amplitudes than normals. Stuporous subjects important changes were observed generally in conjunction with modifications in background activity indicative of changes in the level of awareness. Effects of same drugs upon visual inflow along primary ands secondary visual pathways were studied in cats. LSD 25 VER changed in pattern as well as in amplitude. An increase in latency of secondary waves was evident. Chlorpromazine provoked an increase of primary response with small doses. Larger doses tended to decrease it and to reach normal amplitude. (Author)
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