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Strickland RA. 
“Isabella Coler Herb, MD: an early leader in anesthesiology”. 
Anesth Analg. 1995 Mar;80(3):600-5.
Abstract
Isabella Herb, MD was the first "physician anesthetist" at the Mayo Clinic in Rochester, NY. Her work included pioneering methods of administration and equipment design for anethetics such as ether, chloroform and ethylene.
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