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Schmidt NB, Maner JK, Zvolensky MJ. 
“Reactivity to challenge with carbon dioxide as a prospective predictor of panic attacks”. 
Psychiatry Res. 2007 May 30;151(1-2):173-6.
Fear responding induced by carbon dioxide was prospectively evaluated as a risk factor for the development of anxiety pathology in a nonclinical sample N=404 followed for 2 years. Baseline response to a CO2 challenge was a very strong predictor of future panic attacks though not for panic disorder or other anxiety disorders.

Key Words: carbogen
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