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Corazza O, Schifano F. 
“Near-death states reported in a sample of 50 misusers”. 
Subst Use Misuse. 2010 May 19;45(6):916-24.
Increase in recreational ketamine use may be a cause for concern. We aimed here at assessing, in a sample of ketamine misusers, concordance between the typical near-death experience NDE features and the on-drug psychoactive effects the subjects experienced. In 2003-2005, a sample of previous ketamine misusers recollecting a ketamine-related NDE were recruited through snowballing and screened with the means of the Greyson NDE Scale 125 participants made an initial contact with the researcher and 50 reported a minimum score of seven at the 'Greyson NDE Scale'. Interviewees were in the range 21-66 years old 27 participants 54 were educated at BA level, 18 36 had an MSc, and 5 10 a PhD. Eight 16 interviewees had a definite religious background. An average lifetime ketamine intake of 140 occasions was reported by the interviewees, who typically presented with a polydrug, including cannabis and MDMA/ecstasy, misuse history. In 45 90 cases, the NDE occurred during the first few occasions of intake. Most frequent features of reported NDE states included: altered perception of time 90, strong sense of detaching from own physical body 88, and a sense of peace/joy 76 of subjects. Although results here described were elicited from a self-selected, nonrandomized, limited size sample of misusers, we suggest that recreational ketamine intake may be associated with occurrence of near-death related states.
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