Erowid.org: Erowid Reference 8226 : The chemorelease of norepinephrine from mouse hearts. Structure-activity relationships. I. Sympathomimetic and related amines : Daly JW, Creveling CR, Witkop B

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Daly JW, Creveling CR, Witkop B. “The chemorelease of norepinephrine from mouse hearts. Structure-activity relationships. I. Sympathomimetic and related amines”. J Med Chem. 1966 May 02;9(3):273-80. <a name="ref">Daly JW, Creveling CR, Witkop B.</a> <a href="/references/8226">"The chemorelease of norepinephrine from mouse hearts. Structure-activity relationships. I. Sympathomimetic and related amines"</a> <i>J Med Chem</i>. 1966 May 02;9(3):273-80.
Text Abstract (this page) Full Text - English (private) Show Articles by Daly JW Creveling CR Witkop B Article IDs Erowid RefID: 8226 PubMedID: 5960887 Collections Hofmann Collection MDMA Collection All References	Abstract A rapid method for determining the chemorelease of cardiac norepinephrine in the mouse has been developed. Endogenous cardiac norepinephrine is prelabeled with 5 ľcuriea of norepinephrine-7-H. The cardiac norepinephrine-H remaining in the heart after 3 hr averages 340 mľcuries. Lower levels of radioactivity are found in heart when animals are injected 1 hr after the norepinephrine-H with a compound that causes chemorelease. The releasing potencies of a wide variety of sympathomimetic araines and related compounds have been determined. Structure-activity correlations are discussed.
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