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Dursun SM, Handley SL, Freeman S. 
“Anti-AIDS agents AZT and TIBO R 82913 reduce 52 -HT receptor-mediated DOI-head-shakes in mice”. 
Journal of Psychopharmacology. 1993;7(2):215-6.
Abstract
5-HT systems, acting through central 5-HT2 receptors, have been implicated in controlling mood, social behaviour, sleep patterns, depression, anxiety and negative symptoms in schizophrenia Leysen and Pauwels,1990. Down-regulation of 5-HT2 receptors also has been reported consistently during dementing processes and dementia Cross et al., 1986 Gross-Isseroff et al.,1990.
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