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Ramos JM Jr, Fitzgerald RL, Poklis A. 
“MDMA and MDA cross reactivity observed with Abbott TDx amphetamine/methamphetamine reagents”. 
Clin Chem. 1988;34(5):991.
Abbott Laboratories has recently introduced a fluorescent polarization immunoassay kit for detection of amphetamine and methamphetamine in urine for use on the Abbott TDx. With these reagents, Abbott has successfully eliminated most of the cross reactivity with other sympathomimetic amines and similar compounds often observed in other immunoassays (1). However, we have noted that the TDx amphetamine/methamphetamine kit does cross react significantly with 3,4-methylenedioxymethamphetamine (MDMA), also known as 'Ecstasy,' and 3,4-methylenedioxyamphetamine (MDA).
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