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Lawn W, Barratt M, Williams M, Horne A, Winstock A. 
“The NBOMe hallucinogenic drug series: Patterns of use, characteristics of users and self-reported effects in a large international sample”. 
J Psychopharmacol. 2014 Feb 26.
The NBOMe compounds are a novel series of hallucinogenic drugs that are potent agonists of the 5-HT2A receptor, have a short history of human consumption and are available to buy online, in most countries. In this study, we sought to investigate the patterns of use, characteristics of users and self-reported effects. A cross-sectional anonymous online survey exploring the patterns of drug use was conducted in 2012 (n = 22,289), including questions about the use of 25B-NBOMe, 25C-NBOMe, and 25I-NBOMe and comparison drugs. We found that 2.6 of respondents (n = 582) reported having ever tried one of the three NBOMe drugs and that at 2.0, 25I-NBOMe was the most popular (n = 442). Almost all (93.5) respondents whose last new drug tried was a NBOMe drug, tried it in 2012, and 81.2 of this group administered the drug orally or sublingually/buccally. Subjective effects were similar to comparison serotonergic hallucinogens, though higher 'negative effects while high' and greater 'value for money' were reported. The most common (41.7) drug source was via a website. The NBOMe drugs have emerged recently, are frequently bought using the internet and have similar effects to other hallucinogenic drugs; however, they may pose larger risks, due to the limited knowledge about them, their relatively low price and availability via the internet.
Comments and Responses to this Article
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Feb 28, 2014 17:40
Do Not Extrapolate from Findings: Weak Methodology, Bad Survey Design #

Unfortunately, all of the work done by the Global Drug Survey has been flawed as of early 2014. The surveys are not representative of any population in particular, the survey questions are poorly designed, and the results are therefore essentially spurious.

It is true that it can be said that many buyers of NBOMe products who filled out their survey bought it online, but that says essentially nothing about the total user population and where most people who take NBOMe compounds get their product.

It is important to keep in mind that their data cannot and should not be extrapolated to the general public or even extrapolate to the people who tried to use their survey, since their survey had no review and reliably turned away participants who simply quit because of software problems, length of survey, and other fundamental survey design flaws.

The authors have, sadly, continued to make fatal design flaws in all of their surveys and have been unwilling to make appropriate changes.
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